Bipolar Disorders Program and INCT Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre CEP 90035-003, Brazil.
Compr Psychiatry. 2012 Apr;53(3):238-44. doi: 10.1016/j.comppsych.2011.04.058. Epub 2011 Jun 2.
The use of crack cocaine is a major public health concern in Brazil and internationally. Recent data suggest that childhood trauma is associated with worse outcomes among cocaine users. This study had the objective of evaluating the relationship of childhood trauma with executive functioning and impulsivity in outpatients with crack cocaine use disorders.
This is a cross-sectional study of 84 consecutive outpatients with a primary crack cocaine use disorder who sought treatment in Porto Alegre, Brazil. Childhood trauma was evaluated with the Childhood Trauma Questionnaire; executive functioning, with the Wisconsin Card Sorting Test; and impulsivity, with the Barratt Impulsivity Scale.
Childhood trauma was strongly associated with executive dysfunction and impulsivity, even when controlled for possible confounders.
Childhood trauma may be associated with executive dysfunction and impulsivity in crack cocaine users. The full impact of trauma needs to be further investigated in longitudinal studies.
在巴西和国际上，吸食快克可卡因是一个主要的公共卫生关注点。最近的数据表明，童年创伤与可卡因使用者的预后较差有关。本研究旨在评估童年创伤与门诊使用快克可卡因障碍患者的执行功能和冲动之间的关系。
这是一项横断面研究，共纳入 84 例连续就诊于巴西阿雷格里港的原发性快克可卡因使用障碍患者。采用童年创伤问卷评估童年创伤；威斯康星卡片分类测验评估执行功能；巴瑞特冲动量表评估冲动性。
即使控制了可能的混杂因素，童年创伤仍与执行功能障碍和冲动性显著相关。
童年创伤可能与快克可卡因使用者的执行功能障碍和冲动性有关。需要在纵向研究中进一步探讨创伤的全部影响。
