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All fibroblasts are equal, but some are more equal than others.

作者信息

Bolton Chrissy, Croft Adam P

机构信息

Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.

Rheumatology Research Group, Queen Elizabeth Hospital, University of Birmingham, Birmingham, UK.

出版信息

Nat Rev Rheumatol. 2024 May;20(5):254-255. doi: 10.1038/s41584-024-01097-6.

DOI:10.1038/s41584-024-01097-6
PMID:38467780
Abstract
摘要

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The long non-coding RNA HOTAIR contributes to joint-specific gene expression in rheumatoid arthritis.长链非编码 RNA HOTAIR 有助于类风湿关节炎的关节特异性基因表达。
Nat Commun. 2023 Dec 9;14(1):8172. doi: 10.1038/s41467-023-44053-w.
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Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.类风湿关节炎滑膜的解构定义了炎症亚型。
Nature. 2023 Nov;623(7987):616-624. doi: 10.1038/s41586-023-06708-y. Epub 2023 Nov 8.
3
Joint-level responses to tofacitinib and methotrexate: a post hoc analysis of data from ORAL Start.
托法替布与甲氨蝶呤的关节反应：来自 ORAL Start 的事后分析数据。
Arthritis Res Ther. 2023 Sep 29;25(1):185. doi: 10.1186/s13075-023-03144-1.
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Patterns of clinical joint inflammation in juvenile idiopathic arthritis.幼年特发性关节炎的临床关节炎症模式。
RMD Open. 2023 Mar;9(1). doi: 10.1136/rmdopen-2022-002941.
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Arthritis flares mediated by tissue-resident memory T cells in the joint.关节组织驻留记忆 T 细胞介导热敏关节炎发作。
Cell Rep. 2021 Oct 26;37(4):109902. doi: 10.1016/j.celrep.2021.109902.
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The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts.补体系统通过滑膜成纤维细胞的代谢重编程驱动局部炎症组织启动。
Immunity. 2021 May 11;54(5):1002-1021.e10. doi: 10.1016/j.immuni.2021.03.003. Epub 2021 Mar 23.
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Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions.表观遗传驱动的滑膜成纤维细胞解剖多样性指导关节特异性成纤维细胞功能。
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Wnt signaling and injury repair.Wnt 信号与损伤修复。
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