Faculty of Science and Technology, Physics Department, Universidad Nacional Pedro Henríquez Ureña, Santo Domingo, Dominican Republic.
Centre for Medical Visualization, National Institute for Bioengineering, INABIO, Universidad Central de Venezuela and Centro de Diagnóstico Docente Las Mercedes, Caracas, Venezuela.
Adv Neurobiol. 2024;36:487-499. doi: 10.1007/978-3-031-47606-8_25.
The dynamics of tumor growth is a very complex process, generally accompanied by numerous chromosomal aberrations that determine its genetic and dynamical heterogeneity. Consequently, the tumor interface exhibits a non-regular and heterogeneous behavior often described by a single fractal dimension. A more suitable approach is to consider the tumor interface as a multifractal object that can be described by a set of generalized fractal dimensions. In the present work, detrended fluctuation and multifractal analysis are used to characterize the complexity of glioblastoma.
肿瘤生长的动力学是一个非常复杂的过程，通常伴随着许多决定其遗传和动力学异质性的染色体畸变。因此，肿瘤界面表现出非规则和不均匀的行为，通常用单个分形维数来描述。一种更合适的方法是将肿瘤界面视为一个多重分形物体，可以用一组广义分形维数来描述。在本工作中，去趋势波动和多重分形分析用于表征胶质母细胞瘤的复杂性。
