Sasada Tsuyoshi, Shirakawa Chigusa, Tachikawa Ryo, Yamashita Daisuke, Tomii Keisuke
Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
Department of Pathology, Kobe City Medical Center General Hospital, Kobe, Japan.
Thorac Cancer. 2024 Apr;15(11):934-937. doi: 10.1111/1759-7714.15277. Epub 2024 Mar 11.
Metastasis from one neoplasm to another is referred to as tumor-to-tumor metastasis (TTM). TTM is rarely observed. Here, we present a patient with TTM from a thymic carcinoma to an ovarian mature teratoma. A 25-year-old woman, diagnosed with unresectable thymic carcinoma, presented with a cyst with a solid tumor component in her right ovary. Laparoscopic cystectomy of the right ovary revealed that the solid tumor was a distant metastasis of the thymic carcinoma in an ovarian mature teratoma. The possibility of malignant transformation of the ovarian mature teratoma was ruled out, enabling accurate staging of the thymic carcinoma. This case emphasizes the need for clinicians to consider TTM and the importance of pathological confirmation of TTM when investigating potential distant metastases.
肿瘤从一个肿瘤转移至另一个肿瘤被称为肿瘤间转移(TTM)。TTM很少见。在此,我们报告一例从胸腺癌转移至卵巢成熟畸胎瘤的TTM患者。一名25岁女性,被诊断为无法切除的胸腺癌,其右卵巢出现一个含有实性肿瘤成分的囊肿。对右卵巢进行腹腔镜囊肿切除术发现,实性肿瘤是胸腺癌在卵巢成熟畸胎瘤中的远处转移。排除了卵巢成熟畸胎瘤恶变的可能性,从而能够对胸腺癌进行准确分期。该病例强调临床医生在调查潜在远处转移时需要考虑TTM以及对TTM进行病理确认的重要性。