Alzahrani Meshari A, Alkhani Khalid O, Alassaf Abdullah M, Alorainy Jehad I, Binsaleh Saleh, Almannie Raed
Department of Urology, College of Medicine, Majmaah University, Al-Majmaah, Saudi Arabia.
College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Front Endocrinol (Lausanne). 2024 Feb 26;14:1226858. doi: 10.3389/fendo.2023.1226858. eCollection 2023.
This extensive comprehensive review explores the impact of the Coronavirus disease 2019 (COVID-19) pandemic on men's sexual and reproductive health. We conducted a literature review focusing on the possible pathophysiology by which severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) affects men's sexual and reproductive systems. We reviewed most of the studies that reported the impact of SARS-CoV-2 infection on the Testicular, Epididymal, Prostatic, and Penile tissue. Also, we focused on evaluating the SARS-CoV-2 infection on semen parameters and male reproductive hormones. Finally, we reviewed the COVID-19 vaccine's effect on male reproductive and sexual health. Findings revealed the adverse consequences of SARS-CoV-2 at cellular and organ levels on the male genital tract. However, the reported data are still controversial. The initial data regarding COVID-19 vaccination was promising promoted safety for men's reproductive and sexual health. We conclude this paper by offering recommendations to address these adverse consequences and potentially improve sexual and reproductive health among men in the post-COVID-19 pandemic era.
这篇广泛的综述探讨了2019年冠状病毒病（COVID-19）大流行对男性性健康和生殖健康的影响。我们进行了一项文献综述，重点关注严重急性呼吸综合征冠状病毒2（SARS-CoV-2）影响男性性和生殖系统的可能病理生理学。我们回顾了大多数报告SARS-CoV-2感染对睾丸、附睾、前列腺和阴茎组织影响的研究。此外，我们专注于评估SARS-CoV-2感染对精液参数和男性生殖激素的影响。最后，我们回顾了COVID-19疫苗对男性生殖和性健康的影响。研究结果揭示了SARS-CoV-2在细胞和器官水平上对男性生殖道的不良后果。然而，所报告的数据仍存在争议。关于COVID-19疫苗接种的初步数据显示对男性生殖和性健康有安全性保障，前景良好。我们通过提出建议来结束本文，以应对这些不良后果，并有可能在COVID-19大流行后时代改善男性的性健康和生殖健康。
