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坏死性肺炎、骨骼肌病变及十二指肠蕈样肿物:快速进展型肺腺癌的非典型表现

Necrotizing Pneumonia, a Skeletal Muscle Lesion, and a Fungating Duodenal Mass: An Atypical Presentation of Rapidly Progressing Lung Adenocarcinoma.

作者信息

Ferkin Justin, Williams Brooke, Moore Phillip S

机构信息

Surgery, Campbell University School of Osteopathic Medicine, Salisbury, USA.

Internal Medicine, Novant Health, Winston-Salem, USA.

出版信息

Cureus. 2024 Feb 10;16(2):e53950. doi: 10.7759/cureus.53950. eCollection 2024 Feb.

Abstract

Lung adenocarcinoma, the predominant subtype of non-small cell lung cancer, typically metastasizes to common sites such as the liver and adrenal glands. However, rare instances involve skeletal muscle metastasis. We present a case of a 45-year-old female with a medical history of hypertension, epilepsy, and fibromyalgia, who presented to the emergency department with hemoptysis and multifocal pain. Chest imaging revealed a cavitary lesion which appeared to be necrotizing pneumonia. Further investigations uncovered a fluid collection in the left thigh, which would be identified as poorly differentiated carcinoma. Subsequent testing identified the lung as the primary source of metastasis. Despite radiation treatment, the patient's condition deteriorated over the next 50 days, highlighting the aggressive nature of the disease.

摘要

肺腺癌是非小细胞肺癌的主要亚型,通常会转移至肝脏和肾上腺等常见部位。然而,罕见情况下会发生骨骼肌转移。我们报告一例45岁女性病例,她有高血压、癫痫和纤维肌痛病史,因咯血和多灶性疼痛就诊于急诊科。胸部影像学检查发现一个空洞性病变,看起来像是坏死性肺炎。进一步检查发现左大腿有液体积聚,后来被确定为低分化癌。后续检测确定肺部是转移的原发部位。尽管进行了放射治疗,但患者的病情在接下来的50天里仍恶化,凸显了该疾病的侵袭性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5c/10926317/2be3b9a6af52/cureus-0016-00000053950-i01.jpg

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