Clin Lab. 2024 Mar 1;70(3). doi: 10.7754/Clin.Lab.2023.230916.
Yokenella regensburgei is a gram-negative, opportunistic pathogen that is ubiquitous in natural environments. It commonly affects immunocompromised patients.
The patient was a 71-year-old female with skin and soft tissue wound caused by trauma. The surgical debridement and abscess drainage were performed by surgeons. The specie of infected organism was identified by the D2Mini semi-automated system and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF).
The result of bacterium culture showed gram-negative bacillus was moist, grey-white, semitransparent, and regular shape. Then the D2Mini semi-automated system and MALDI-TOF revealed that the colonies are Y. regensburgei. According to the result for drug sensitivity, antibiotic therapy was switched to cefoperazone/sulbac-tam and levofloxacin.
Cooperation between clinical microbiology laboratories and surgeons is essential for the infected patient without typical symptoms. Agricultural activities and stab wounds may be related to Y. regensburgei infection.
约科奈拉雷根斯堡菌是一种革兰氏阴性、机会性病原体，广泛存在于自然环境中。它通常影响免疫功能低下的患者。
患者为 71 岁女性，因外伤导致皮肤和软组织伤口。外科医生进行了手术清创和脓肿引流。感染的生物体种类通过 D2Mini 半自动系统和基质辅助激光解吸/电离飞行时间质谱（MALDI-TOF）进行鉴定。
细菌培养结果显示革兰氏阴性杆菌呈湿润、灰白色、半透明、规则形状。然后 D2Mini 半自动系统和 MALDI-TOF 显示该菌落为约科奈拉雷根斯堡菌。根据药敏结果，抗生素治疗改为头孢哌酮/舒巴坦和左氧氟沙星。
对于没有典型症状的感染患者，临床微生物学实验室和外科医生之间的合作至关重要。农业活动和刺伤可能与约科奈拉雷根斯堡菌感染有关。
