V Annie Sheeba, Suji Thangamani, Jayanth Selvin Theodore, Sahni Rani Diana
Department of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
Department of Urology, Christian Medical College, Vellore, Tamil Nadu, India.
Access Microbiol. 2023 Oct 17;5(10). doi: 10.1099/acmi.0.000571.v4. eCollection 2023.
, belonging to the order , is a rare and emerging human pathogen reported to cause both superficial and invasive infections. The 13 case reports in the literature worldwide highlight blood, bone and wound infections. To our knowledge this is the first case description of causing a urinary tract infection in a 69-year-old immunocompetent patient which was isolated in two separate specimens and identified using matrix-assisted laser desorption ionization time-of-flight MS. It was found to be susceptible to most antimicrobials but resistant to penicillin, amoxicillin-clavulanate, cefoxitin and colistin. Inducible chromosomal resistance was demonstrated on disc approximation testing, and YOC-1 class C beta-lactamase, beta lactamase superfamily and MBL fold metallo-hydrolase genes were found on whole genome sequencing.
属于 目，是一种罕见的新兴人类病原体，据报道可引起浅表和侵袭性感染。全球文献中的13例病例报告突出了血液、骨骼和伤口感染。据我们所知，这是首例关于 在一名69岁免疫功能正常患者中引起尿路感染的病例描述，该病原体在两个独立样本中分离出来，并使用基质辅助激光解吸电离飞行时间质谱进行鉴定。发现它对大多数抗菌药物敏感，但对青霉素、阿莫西林-克拉维酸、头孢西丁和黏菌素耐药。纸片扩散法检测显示有诱导性染色体 耐药，全基因组测序发现了YOC-1 C类β-内酰胺酶、β-内酰胺酶超家族和MBL折叠金属水解酶基因。
