AlMutawa Fatimah, Kim Sang Ho, Cabrera Ana, Delport Johan
Department of Pathology and Laboratory Medicine, Western University, London, Ontario, Canada.
London Health Sciences Centre, London, Ontario, Canada.
J Assoc Med Microbiol Infect Dis Can. 2023 Mar 1;8(1):94-98. doi: 10.3138/jammi-2022-0018. eCollection 2023 Mar.
infections have been documented in several immunocompromised individuals with numerous associated risk factors including soft tissue infections, organ transplants, and metabolic disorders. Our report presents a rare case of Y. infection in an immunocompetent individual.
In September 2020, a 38-year-old man who was otherwise healthy fell from a personal conveyance causing a puncture of his elbow. Two months later, he was admitted to the hospital with a chronic draining wound on his left arm with no fever (36.7°C) and stable vital signs. The patient underwent white blood cell (WBC) imaging, and single-photon emission computed tomography (SPECT/CT) to rule out osteomyelitis. Incision and drainage were performed, and the collected fluid was sent to a microbiology lab for culture diagnosis. Subsequently, matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) analysis and antimicrobial susceptibility testing were performed.
A WBC image and SPECT/CT test showed an increase in WBC uptake and activity in the subcutaneous tissue of the left arm. The culture diagnosis identified the isolate as and the patient received 2 weeks of sulfamethoxazole 800 mg and trimethoprim 160 mg orally twice daily based on the results of the antimicrobial susceptibility testing. He demonstrated clinical improvements shown through wound healing and reduced pain.
This report supports the potential of to act as an opportunistic pathogen even in hosts with no prior underlying diseases or conditions.
在一些具有多种相关风险因素的免疫功能低下个体中已记录到感染情况，这些因素包括软组织感染、器官移植和代谢紊乱。我们的报告展示了一例免疫功能正常个体感染耶尔森菌的罕见病例。
2020年9月，一名原本健康的38岁男子从个人交通工具上跌落，导致肘部穿刺伤。两个月后，他因左臂慢性引流伤口入院，无发热（36.7°C），生命体征稳定。患者接受了白细胞（WBC）成像和单光子发射计算机断层扫描（SPECT/CT）以排除骨髓炎。进行了切开引流，并将收集的液体送往微生物实验室进行培养诊断。随后，进行了基质辅助激光解吸/电离飞行时间（MALDI-TOF）分析和抗菌药敏试验。
白细胞成像和SPECT/CT检查显示左臂皮下组织中白细胞摄取和活性增加。培养诊断确定分离株为[具体细菌名称未给出]，根据抗菌药敏试验结果，患者接受了为期2周的磺胺甲恶唑800mg和甲氧苄啶160mg口服，每日两次。他通过伤口愈合和疼痛减轻表现出临床改善。
本报告支持即使在没有先前基础疾病或状况的宿主中，[具体细菌名称未给出]也有作为机会性病原体的可能性。
