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通过优化的柔性超表面实现 7T 下小牛 MRI 的体内增强。

In vivo enhancement of calf MRI at 7 T via optimized flexible metasurfaces.

机构信息

Center for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Magnetic Detection and Imaging group, TechMed Centre, University of Twente, Enschede, The Netherlands.

出版信息

Magn Reson Med. 2024 Sep;92(3):1277-1289. doi: 10.1002/mrm.30060. Epub 2024 Mar 12.

Abstract

PURPOSE

Ultrahigh field (≥7 T) MRI is at the cutting edge of medical imaging, enabling enhanced spatial and spectral resolution as well as enhanced susceptibility contrast. However, transmit ( ) field inhomogeneity due to standing wave effects caused by the shortened RF wavelengths at 7 T is still a challenge to overcome. Novel hardware methods such as dielectric pads have been shown to improve the field inhomogeneity but are currently limited in their corrective effect by the range of high-permittivity materials available and have a fixed shelf life. In this work, an optimized metasurface design is presented that demonstrates in vivo enhancement of the field.

METHODS

A prototype metasurface was optimized by an empirical capacitor sweep and by varying the period size. Phantom temperature experiments were performed to evaluate potential metasurface heating effects during scanning. Lastly, in vivo gradient echo images and maps were acquired on five healthy subjects on a 7 T system. Dielectric pads were also used as a comparison throughout the work as a standard comparison.

RESULTS

The metasurfaces presented here enhanced the average relative SNR of the gradient echo images by a factor of 2.26 compared to the dielectric pads factor of 1.61. Average values reflected a similar enhancement of 27.6% with the metasurfaces present versus 8.9% with the dielectric pads.

CONCLUSION

The results demonstrate that metasurfaces provide superior performance to dielectric padding as shown by maps reflecting their direct effects and resulting enhancements in image SNR at 7 T.

摘要

目的

超高场(≥7T)MRI 处于医学成像的前沿,能够提高空间和光谱分辨率以及磁化率对比。然而,由于 7T 时射频波长缩短而产生的驻波效应导致的( )场不均匀性仍然是一个需要克服的挑战。已经证明,像介电垫这样的新型硬件方法可以改善( )场不均匀性,但目前由于高介电常数材料的可用范围,其校正效果有限,并且具有固定的保质期。在这项工作中,提出了一种优化的超表面设计,证明了在体内增强( )场。

方法

通过经验电容扫描和改变周期大小来优化原型超表面。进行了幻影温度实验以评估在扫描过程中可能存在的超表面加热效应。最后,在 7T 系统上对五名健康受试者进行了梯度回波图像和( )图采集。在整个工作中,介电垫也被用作标准比较。

结果

与介电垫的增强因子 1.61 相比,这里提出的超表面将梯度回波图像的平均相对 SNR 提高了 2.26 倍。平均( )值反映了类似的增强,带有超表面的增强了 27.6%,而带有介电垫的增强了 8.9%。

结论

结果表明,超表面提供了优于介电垫的性能,这反映在( )图中,反映了它们的直接影响以及在 7T 时图像 SNR 的增强。

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Flexible metasurface for improving brain imaging at 7T.用于改善 7T 脑成像的灵活超表面
Magn Reson Med. 2024 Aug;92(2):869-880. doi: 10.1002/mrm.30088. Epub 2024 Mar 12.

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