Centre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Division of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Murcia, Spain.
Suicide Life Threat Behav. 2024 Jun;54(3):606-614. doi: 10.1111/sltb.13071. Epub 2024 Mar 12.
This study aimed to investigate the association between handgrip strength and suicidal ideation in representative samples of adults aged ≥50 years from six LMICs (China, Ghana, India, Mexico, Russia, and South Africa).
Cross-sectional, community-based data from the World Health Organization's Study on Global Aging and Adult Health were analyzed. Handgrip strength quintiles by sex were created based on the average value of two handgrip measurements of the dominant hand. Self-reported information on past 12-month suicidal ideation was collected. Multivariable logistic regression analysis was conducted to assess associations.
Data on 34,129 individuals were analyzed [mean (SD) age 62.4 (16.0) years; age range 50-114 years; 52.1% females]. After adjustment for potential confounders, in the overall sample, compared to the handgrip strength quintile with the highest values [Quintile 1 (Q1)], Q2, Q3, Q4, and Q5 were associated with significant 2.15 (95% CI = 1.05-4.39), 2.78 (95% CI = 1.06-7.32), 3.53 (95% CI = 1.68-7.42), and 6.79 (95% CI = 2.80-16.48) times higher odds for suicidal ideation.
Lower handgrip strength was significantly and dose-dependently associated with higher odds for suicidal ideation in adults aged ≥50 years from LMICs. Future longitudinal studies are needed to understand the underlying mechanisms, and whether increasing general muscular strength and physical function may lead to reduction in suicidal ideation.
本研究旨在调查握力与来自六个中低收入国家（中国、加纳、印度、墨西哥、俄罗斯和南非）≥50 岁成年人自杀意念之间的关联。
对世界卫生组织全球老龄化和成人健康研究的横断面、社区为基础的数据进行了分析。根据惯用手握力的两次测量的平均值，按性别创建了握力五分位数。收集了过去 12 个月自杀意念的自我报告信息。采用多变量逻辑回归分析评估相关性。
共分析了 34129 名参与者的数据（平均年龄 62.4[16.0]岁；年龄范围 50-114 岁；女性占 52.1%）。在调整了潜在混杂因素后，在整个样本中，与握力最强的五分位数（五分位 1[Q1]）相比，五分位 2、3、4 和 5 与自杀意念的显著相关性分别为 2.15（95%CI=1.05-4.39）、2.78（95%CI=1.06-7.32）、3.53（95%CI=1.68-7.42）和 6.79（95%CI=2.80-16.48）。
在来自中低收入国家的≥50 岁成年人中，握力较低与自杀意念的几率显著呈剂量依赖性相关。需要进一步开展前瞻性研究，以了解潜在机制，以及增加一般肌肉力量和身体功能是否可以降低自杀意念。
