Centre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Division of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Murcia, Spain.
J Gerontol B Psychol Sci Soc Sci. 2024 Sep 1;79(9). doi: 10.1093/geronb/gbae129.
Mild cognitive impairment (MCI) is a unique indicator of underlying distress that may be strongly associated with suicide risk. Despite this, to date, no study has examined the association between MCI and suicidal ideation. Therefore, the present study aimed to examine the association between MCI and suicidal ideation among adults aged ≥65 years from 6 low- and middle-income countries (LMICs; China, Ghana, India, Mexico, Russia, and South Africa).
Cross-sectional, nationally representative data from the World Health Organization's Study on Global Ageing and Adult Health were analyzed. MCI was defined using the National Institute on Aging-Alzheimer's Association criteria. Self-reported information on past 12-month suicidal ideation was collected. Multivariable logistic regression and meta-analysis were conducted to assess associations.
Data on 13,623 individuals aged ≥65 years were analyzed. The prevalence of suicidal ideation ranged from 0.5% in China to 6.0% in India, whereas the range of the prevalence of MCI was 9.7% (Ghana) to 26.4% (China). After adjustment for potential confounders, MCI was significantly associated with 1.66 (95% confidence interval [95% CI] = 1.12-2.46) times higher odds for suicidal ideation.
Mild cognitive impairment was significantly associated with higher odds for suicidal ideation among older adults in LMICs. Future longitudinal studies from LMICs are necessary to assess whether MCI is a risk factor for suicidal ideation.
轻度认知障碍（MCI）是一种潜在痛苦的独特指标，可能与自杀风险密切相关。尽管如此，迄今为止，尚无研究探讨 MCI 与自杀意念之间的关系。因此，本研究旨在检验 6 个中低收入国家（中国、加纳、印度、墨西哥、俄罗斯和南非）≥65 岁成年人中 MCI 与自杀意念之间的关系。
对世界卫生组织全球老龄化和成人健康研究的横断面、全国代表性数据进行分析。采用美国国家老龄化研究所-阿尔茨海默病协会标准定义 MCI。收集过去 12 个月自杀意念的自我报告信息。采用多变量逻辑回归和荟萃分析评估相关性。
共分析了 13623 名≥65 岁个体的数据。自杀意念的患病率在中国为 0.5%，在印度为 6.0%，而 MCI 的患病率范围在中国为 9.7%，在加纳为 26.4%。调整潜在混杂因素后，MCI 与自杀意念的比值比显著相关，为 1.66（95%置信区间[95%CI]为 1.12-2.46）。
MCI 与中低收入国家老年人自杀意念的可能性增加显著相关。需要从中低收入国家开展未来的纵向研究，以评估 MCI 是否是自杀意念的一个风险因素。
