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照顾者对自我护理的贡献与心力衰竭患者生活质量之间的关系:纵向中介分析。

The relationship between caregiver contribution to self-care and patient quality of life in heart failure: A longitudinal mediation analysis.

机构信息

San Giovanni Addolorata Hospital, Rome, Italy.

Department of Psychology of Development and Socialization processes, "Sapienza" University of Rome, Rome, Italy.

出版信息

PLoS One. 2024 Mar 12;19(3):e0300101. doi: 10.1371/journal.pone.0300101. eCollection 2024.

Abstract

BACKGROUND

Patients with heart failure may experience poor quality of life due to a variety of physical and psychological symptoms. Quality of life can improve if patients adhere to consistent self-care behaviors. Patient outcomes (i.e., quality of life) are thought to improve as a result of caregiver contribution to self-care. However, uncertainty exists on whether these outcomes improve as a direct result of caregiver contribution to self-care or whether this improvement occurs indirectly through the improvement of patient heart failure self-care behaviors.

AIMS

To investigate the influence of caregiver contribution to self-care on quality of life of heart failure people and explore whether patient self-care behaviors mediate such a relationship.

METHODS

This is a secondary analysis of the MOTIVATE-HF randomized controlled trial (Clinicaltrials.gov registration number: NCT02894502). Data were collected at baseline and 3 months. An autoregressive longitudinal path analysis model was conducted to test our hypotheses.

RESULTS

We enrolled a sample of 510 caregivers [mean age = 54 (±15.44), 24% males)] and 510 patients [mean age = 72.4 (±12.28), 58% males)]. Patient self-care had a significant and direct effect on quality of life at three months (β = 0.20, p < .01). Caregiver contribution to self-care showed a significant direct effect on patient self-care (β = 0.32, p < .01), and an indirect effect on patient quality of life through the mediation of patient self-care (β = 0.07, p < .001).

CONCLUSION

Patient quality of life is influenced by self-care both directly and indirectly, through the mediation of caregiver contribution to self-care. These findings improve our understanding on how caregiver contribution to self-care improves patient outcomes.

摘要

背景

心力衰竭患者可能会因各种身体和心理症状而导致生活质量下降。如果患者坚持一致的自我护理行为,生活质量可以得到改善。患者的结局(即生活质量)被认为会因照顾者对自我护理的贡献而得到改善。然而,尚不确定这些结局是直接因照顾者对自我护理的贡献而改善,还是通过改善患者心力衰竭自我护理行为而间接改善。

目的

探讨照顾者对自我护理的贡献对心力衰竭患者生活质量的影响,并探讨患者自我护理行为是否在其中起中介作用。

方法

这是 MOTIVATE-HF 随机对照试验(Clinicaltrials.gov 注册号:NCT02894502)的二次分析。数据收集于基线和 3 个月时。采用自回归纵向路径分析模型检验我们的假设。

结果

我们纳入了 510 名照顾者(平均年龄 = 54(±15.44)岁,24%为男性)和 510 名患者(平均年龄 = 72.4(±12.28)岁,58%为男性)。患者自我护理对 3 个月时的生活质量有显著的直接影响(β = 0.20,p <.01)。照顾者对自我护理的贡献对患者自我护理有显著的直接影响(β = 0.32,p <.01),并通过患者自我护理的中介作用对患者生活质量产生间接影响(β = 0.07,p <.001)。

结论

患者的生活质量受到自我护理的直接和间接影响,通过照顾者对自我护理的贡献的中介作用。这些发现提高了我们对照顾者对自我护理的贡献如何改善患者结局的理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf3a/10931462/182151692462/pone.0300101.g001.jpg

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