Wexler H, Carter W T, Harris B H, Finegold S M
Antimicrob Agents Chemother. 1985 Apr;27(4):674-6. doi: 10.1128/AAC.27.4.674.
The in vitro activity of cefbuperazone was compared with that of cefoxitin, moxalactam, and piperacillin against 305 strains of anaerobic bacteria. Piperacillin was the most active overall, inhibiting 97% of all anaerobes tested at 128 micrograms/ml. Cefbuperazone had poor activity against the Bacteroides fragilis group and Clostridium difficile (43 and 0% susceptible, respectively) but good activity (90.5%) against all other anaerobic bacterial species tested.
将头孢哌酮的体外活性与头孢西丁、拉氧头孢和哌拉西林对305株厌氧菌的活性进行了比较。哌拉西林总体活性最强,在128微克/毫升时能抑制97%的受试厌氧菌。头孢哌酮对脆弱拟杆菌群和艰难梭菌的活性较差(分别为43%和0%敏感),但对所有其他受试厌氧菌具有良好活性(90.5%)。