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头孢哌酮对厌氧菌的体外活性。

In vitro activity of cefbuperazone against anaerobic bacteria.

作者信息

Wexler H, Carter W T, Harris B H, Finegold S M

出版信息

Antimicrob Agents Chemother. 1985 Apr;27(4):674-6. doi: 10.1128/AAC.27.4.674.

DOI:10.1128/AAC.27.4.674
PMID:3847274
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC180124/
Abstract

The in vitro activity of cefbuperazone was compared with that of cefoxitin, moxalactam, and piperacillin against 305 strains of anaerobic bacteria. Piperacillin was the most active overall, inhibiting 97% of all anaerobes tested at 128 micrograms/ml. Cefbuperazone had poor activity against the Bacteroides fragilis group and Clostridium difficile (43 and 0% susceptible, respectively) but good activity (90.5%) against all other anaerobic bacterial species tested.

摘要

将头孢哌酮的体外活性与头孢西丁、拉氧头孢和哌拉西林对305株厌氧菌的活性进行了比较。哌拉西林总体活性最强,在128微克/毫升时能抑制97%的受试厌氧菌。头孢哌酮对脆弱拟杆菌群和艰难梭菌的活性较差(分别为43%和0%敏感),但对所有其他受试厌氧菌具有良好活性(90.5%)。

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本文引用的文献

1
Comparative in vitro activities of cefpiramide and apalcillin against anaerobic bacteria.头孢匹胺与阿洛西林对厌氧菌的体外比较活性
Antimicrob Agents Chemother. 1984 Feb;25(2):162-4. doi: 10.1128/AAC.25.2.162.
2
Antimicrobial therapy for anaerobic infections.
Scand J Gastroenterol Suppl. 1984;91:61-72.