黑色素瘤、基底细胞癌和鳞状细胞癌的风险因素及风险评估创新
Risk Factors and Innovations in Risk Assessment for Melanoma, Basal Cell Carcinoma, and Squamous Cell Carcinoma.
作者信息
Wunderlich K, Suppa M, Gandini S, Lipski J, White J M, Del Marmol V
机构信息
Department of Dermatology, Hôpital Erasme, Université Libre de Bruxelles, 1070 Brussels, Belgium.
Department of Dermatology, Institute Jules Bordet, Université Libre de Bruxelles, 1070 Brussels, Belgium.
出版信息
Cancers (Basel). 2024 Feb 29;16(5):1016. doi: 10.3390/cancers16051016.
Skin cancer is the most frequently diagnosed cancer globally and is preventable. Various risk factors contribute to different types of skin cancer, including melanoma, basal cell carcinoma, and squamous cell carcinoma. These risk factors encompass both extrinsic, such as UV exposure and behavioral components, and intrinsic factors, especially involving genetic predisposition. However, the specific risk factors vary among the skin cancer types, highlighting the importance of precise knowledge to facilitate appropriate early diagnosis and treatment for at-risk individuals. Better understanding of the individual risk factors has led to the development of risk scores, allowing the identification of individuals at particularly high risk. These advances contribute to improved prevention strategies, emphasizing the commitment to mitigating the impact of skin cancer.
皮肤癌是全球最常被诊断出的癌症，且是可预防的。多种风险因素导致不同类型的皮肤癌，包括黑色素瘤、基底细胞癌和鳞状细胞癌。这些风险因素既包括外在因素，如紫外线暴露和行为因素，也包括内在因素，特别是涉及遗传易感性。然而，具体的风险因素在不同类型的皮肤癌中有所不同，这凸显了准确了解这些因素对于促进对高危个体进行适当的早期诊断和治疗的重要性。对个体风险因素的更好理解促使了风险评分的发展，从而能够识别出特别高危的个体。这些进展有助于改进预防策略，强调了减轻皮肤癌影响的决心。
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