• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

前进之路:胸腺瘤和胸腺癌数十年癌症研究的经验教训

The Way Ahead: Lessons Learned from Decades of Cancer Research on Thymomas and Thymic Carcinomas.

作者信息

Ströbel Philipp, Marx Alexander

机构信息

Institute of Pathology, University Medical Center Göttingen, D-37075 Göttingen, Germany.

出版信息

Cancers (Basel). 2024 Mar 4;16(5):1040. doi: 10.3390/cancers16051040.

DOI:10.3390/cancers16051040
PMID:38473397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10930696/
Abstract

The history of thymoma (TH) research begins in the early 20th century, when Bell first recognized the epithelial nature of these tumors and their association with myasthenia gravis (MG) [...].

摘要

胸腺瘤(TH)的研究历史始于20世纪初,当时贝尔首次认识到这些肿瘤的上皮性质及其与重症肌无力(MG)的关联[...]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfd5/10930696/19615be83a95/cancers-16-01040-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfd5/10930696/19615be83a95/cancers-16-01040-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfd5/10930696/19615be83a95/cancers-16-01040-g001.jpg

相似文献

1
The Way Ahead: Lessons Learned from Decades of Cancer Research on Thymomas and Thymic Carcinomas.前进之路:胸腺瘤和胸腺癌数十年癌症研究的经验教训
Cancers (Basel). 2024 Mar 4;16(5):1040. doi: 10.3390/cancers16051040.
2
Clinical characteristics, prognostic factors, and long-term outcomes associated with epithelial malignancies of the thymus: A 20-year single-institution experience.胸腺上皮性恶性肿瘤的临床特征、预后因素及长期预后:20 年单中心经验。
Cancer Rep (Hoboken). 2023 Mar;6(3):e1750. doi: 10.1002/cnr2.1750. Epub 2022 Nov 12.
3
Somatic mutations of thymic epithelial tumors with myasthenia gravis.伴有重症肌无力的胸腺上皮肿瘤的体细胞突变
Front Oncol. 2023 Aug 21;13:1224491. doi: 10.3389/fonc.2023.1224491. eCollection 2023.
4
Flow cytometric study of lymphocytes associated with thymoma and other thymic tumors.胸腺瘤及其他胸腺肿瘤相关淋巴细胞的流式细胞术研究
J Surg Res. 1999 Apr;82(2):312-8. doi: 10.1006/jsre.1998.5547.
5
Clinical and pathological aspects of microscopic thymoma with myasthenia gravis and review of published reports.合并重症肌无力的微小胸腺瘤的临床及病理特征并文献复习
J Thorac Dis. 2017 Jun;9(6):1592-1597. doi: 10.21037/jtd.2017.05.22.
6
Thymic carcinoma arising in thymoma is associated with alterations in immunohistochemical profile.胸腺瘤中发生的胸腺癌与免疫组化特征的改变有关。
Am J Surg Pathol. 1998 Dec;22(12):1474-81. doi: 10.1097/00000478-199812000-00004.
7
[Expression of CD20 in thymomas and its clinical implication].[CD20在胸腺瘤中的表达及其临床意义]
Zhonghua Bing Li Xue Za Zhi. 2010 Sep;39(9):611-4.
8
Pathological Findings in Myasthenia Gravis Patients with Thymic Hyperplasia and Thymoma.重症肌无力合并胸腺增生和胸腺瘤患者的病理表现
Pathol Oncol Res. 2018 Jan;24(1):67-74. doi: 10.1007/s12253-017-0213-7. Epub 2017 Mar 15.
9
Clinical and pathological aspects of thymic epithelial tumors.胸腺上皮肿瘤的临床与病理特征
Gen Thorac Cardiovasc Surg. 2008 Jan;56(1):10-6. doi: 10.1007/s11748-007-0177-8. Epub 2008 Jan 22.
10
Pathologic Finding of Thymic Carcinoma Accompanied by Myasthenia Gravis.伴有重症肌无力的胸腺癌的病理发现
J Clin Neurol. 2015 Oct;11(4):372-5. doi: 10.3988/jcn.2015.11.4.372. Epub 2015 Aug 21.

引用本文的文献

1
Cell Culture Models for Translational Research on Thymomas and Thymic Carcinomas: Current Status and Future Perspectives.胸腺瘤和胸腺癌转化研究的细胞培养模型:现状与未来展望
Cancers (Basel). 2024 Aug 4;16(15):2762. doi: 10.3390/cancers16152762.

本文引用的文献

1
Human thymoma-associated mutation of the GTF2I transcription factor impairs thymic epithelial progenitor differentiation in mice.人类胸腺瘤相关转录因子 GTF2I 突变可损害小鼠胸腺上皮祖细胞分化。
Commun Biol. 2022 Sep 29;5(1):1037. doi: 10.1038/s42003-022-04002-7.
2
A Knock-In Mouse Model of Thymoma With the GTF2I L424H Mutation.GTF2I L424H 突变致胸腺瘤的嵌合小鼠模型。
J Thorac Oncol. 2022 Dec;17(12):1375-1386. doi: 10.1016/j.jtho.2022.08.008. Epub 2022 Aug 30.
3
Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma.
胸腺瘤中骨髓胸腺上皮细胞导致重症肌无力特异性异常神经肌肉基因表达。
Nat Commun. 2022 Jul 22;13(1):4230. doi: 10.1038/s41467-022-31951-8.
4
RADIORYTHMIC: Phase III, Opened, Randomized Study of Postoperative Radiotherapy Versus Surveillance in Stage IIb/III of Masaoka Koga Thymoma after Complete Surgical Resection.放化疗与观察:完全手术后 IIb/III 期 Masaoka-Koga 胸腺瘤患者术后放疗与观察的 III 期开放随机研究。
Clin Lung Cancer. 2021 Sep;22(5):469-472. doi: 10.1016/j.cllc.2021.01.020. Epub 2021 Feb 4.
5
A Tuft Cell-Like Signature Is Highly Prevalent in Thymic Squamous Cell Carcinoma and Delineates New Molecular Subsets Among the Major Lung Cancer Histotypes.一簇细胞样特征在胸腺癌中高度普遍存在,并在主要肺癌组织类型中划定了新的分子亚型。
J Thorac Oncol. 2021 Jun;16(6):1003-1016. doi: 10.1016/j.jtho.2021.02.008. Epub 2021 Feb 17.
6
High-throughput screening identifies histone deacetylase inhibitors that modulate GTF2I expression in 7q11.23 microduplication autism spectrum disorder patient-derived cortical neurons.高通量筛选鉴定出组蛋白去乙酰化酶抑制剂,可调节 7q11.23 微重复自闭症谱系障碍患者来源的皮质神经元中的 GTF2I 表达。
Mol Autism. 2020 Nov 19;11(1):88. doi: 10.1186/s13229-020-00387-6.
7
Image-based ex vivo drug screen to assess targeted therapies in recurrent thymoma.基于图像的体外药物筛选以评估复发性胸腺瘤的靶向治疗
Lung Cancer. 2020 Jul;145:27-32. doi: 10.1016/j.lungcan.2020.04.036. Epub 2020 May 4.
8
Testing the Efficiency and Kinetics of Negative Selection Using Thymic Slices.使用胸腺切片检测阴性选择的效率和动力学。
Methods Mol Biol. 2020;2111:205-219. doi: 10.1007/978-1-0716-0266-9_17.
9
Identification of potential agents for thymoma by integrated analyses of differentially expressed tumour-associated genes and molecular docking experiments.通过差异表达的肿瘤相关基因综合分析和分子对接实验鉴定胸腺瘤的潜在药物
Exp Ther Med. 2019 Sep;18(3):2001-2014. doi: 10.3892/etm.2019.7817. Epub 2019 Jul 26.
10
The Integrated Genomic Landscape of Thymic Epithelial Tumors.胸腺癌的综合基因组景观。
Cancer Cell. 2018 Feb 12;33(2):244-258.e10. doi: 10.1016/j.ccell.2018.01.003.