Science Club, Faculty of Medicine, Medical University of Lublin, 20-059 Lublin, Poland.
Department of Biochemistry and General Chemistry, Medical College of The Rzeszów University, 35-959 Rzeszów, Poland.
Int J Mol Sci. 2024 Mar 4;25(5):2974. doi: 10.3390/ijms25052974.
Cardiovascular diseases are the third most common cause of death in the world. The most common are heart attacks and stroke. Cardiovascular diseases are a global problem monitored by many centers, including the World Health Organization (WHO). Atherosclerosis is one aspect that significantly influences the development and management of cardiovascular diseases. Photodynamic therapy (PDT) is one of the therapeutic methods used for various types of inflammatory, cancerous and non-cancer diseases. Currently, it is not practiced very often in the field of cardiology. It is most often practiced and tested experimentally under in vitro experimental conditions. In clinical practice, the use of PDT is still rare. The aim of this review was to characterize the effectiveness of PDT in the treatment of cardiovascular diseases. Additionally, the most frequently used photosensitizers in cardiology are summarized.
心血管疾病是世界上第三大常见的死亡原因。最常见的是心脏病发作和中风。心血管疾病是许多中心监测的全球性问题，包括世界卫生组织（WHO）。动脉粥样硬化是显著影响心血管疾病发展和管理的一个方面。光动力疗法（PDT）是用于治疗各种类型的炎症、癌症和非癌症疾病的治疗方法之一。目前，它在心脏病学领域并不经常实践。它最常在体外实验条件下进行实验和测试。在临床实践中，PDT 的应用仍然很少。本综述的目的是描述 PDT 在治疗心血管疾病方面的有效性。此外，还总结了心脏病学中最常使用的光敏剂。
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