• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

用于共价连接的铅传感器吖啶酮冠醚的合成修饰及其对选择性的影响。

Synthetic Modifications of a Pb-Sensor Acridono-Crown Ether for Covalent Attachment and Their Effects on Selectivity.

作者信息

Vezse Panna, Gede Martin, Golcs Ádám, Huszthy Péter, Tóth Tünde

机构信息

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Szent Gellért Sq. 4, H-1111 Budapest, Hungary.

Advanced Membranes and Porous Materials Center, Physical Science and Engineering Division, King Abdullah University of Science and Technology, Thuwal 23955-6900, Saudi Arabia.

出版信息

Molecules. 2024 Mar 1;29(5):1121. doi: 10.3390/molecules29051121.

DOI:10.3390/molecules29051121
PMID:38474633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10935152/
Abstract

Because of environmental impact, there is a great need for chemosensors, especially for toxic heavy metals such as lead. The conventional instrumental analytical techniques rarely provide an available real-time sensing platform, thus the development of highly selective and stable synthetic chemosensor molecules is of great importance. Acridono-18-crown-6 ethers have such properties, and much research has proven their outstanding applicability in various supramolecular devices. In this present work, we aimed to enable their covalent immobilization capability by synthesizing functionalized derivatives while preserving the favored molecular recognition ability. Several new macrocycle analogues were synthesized, while synthetization difficulties and design aspects were also dealt with. The selectivity of the macrocycle analogues was studied using UV-Vis spectroscopy and compared with that of the parent compounds. The ultimate crown ether derivative showed high Pb-selectivity, reversibility (decomplexation by extraction with water) and stability.

摘要

由于环境影响，对化学传感器有很大需求，尤其是对于铅等有毒重金属的传感器。传统的仪器分析技术很少能提供可用的实时传感平台，因此开发高选择性和稳定的合成化学传感器分子非常重要。吖啶并 - 18 - 冠 - 6醚具有这样的特性，许多研究已证明它们在各种超分子器件中具有出色的适用性。在本工作中，我们旨在通过合成功能化衍生物来实现它们的共价固定能力，同时保留其良好的分子识别能力。合成了几种新的大环类似物，同时也处理了合成困难和设计方面的问题。使用紫外 - 可见光谱研究了大环类似物的选择性，并与母体化合物的选择性进行了比较。最终的冠醚衍生物表现出高铅选择性、可逆性（通过用水萃取进行解络合）和稳定性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/f1b55386b36d/molecules-29-01121-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/82b1e4831111/molecules-29-01121-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/1da48fbee2b0/molecules-29-01121-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/a6ffb6435e31/molecules-29-01121-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/f1185ccbb287/molecules-29-01121-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/a5db2a33fe0e/molecules-29-01121-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/907df677513a/molecules-29-01121-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/01c7ecc5e89c/molecules-29-01121-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/01a57469f0ee/molecules-29-01121-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/ac0c8415b99f/molecules-29-01121-sch003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/15260bad56c2/molecules-29-01121-sch004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/6658be682284/molecules-29-01121-sch005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/d7d80b7590f1/molecules-29-01121-sch006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/6669e5878084/molecules-29-01121-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/f1b55386b36d/molecules-29-01121-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/82b1e4831111/molecules-29-01121-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/1da48fbee2b0/molecules-29-01121-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/a6ffb6435e31/molecules-29-01121-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/f1185ccbb287/molecules-29-01121-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/a5db2a33fe0e/molecules-29-01121-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/907df677513a/molecules-29-01121-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/01c7ecc5e89c/molecules-29-01121-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/01a57469f0ee/molecules-29-01121-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/ac0c8415b99f/molecules-29-01121-sch003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/15260bad56c2/molecules-29-01121-sch004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/6658be682284/molecules-29-01121-sch005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/d7d80b7590f1/molecules-29-01121-sch006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/6669e5878084/molecules-29-01121-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/10935152/f1b55386b36d/molecules-29-01121-g008.jpg

相似文献

1
Synthetic Modifications of a Pb-Sensor Acridono-Crown Ether for Covalent Attachment and Their Effects on Selectivity.用于共价连接的铅传感器吖啶酮冠醚的合成修饰及其对选择性的影响。
Molecules. 2024 Mar 1;29(5):1121. doi: 10.3390/molecules29051121.
2
Optically active crown ether-based fluorescent sensor molecules: A mini-review.基于冠醚的旋光性荧光传感器分子：一篇综述。
Chirality. 2019 Feb;31(2):97-109. doi: 10.1002/chir.23031. Epub 2018 Dec 28.
3
Fast Potentiometric Analysis of Lead in Aqueous Medium under Competitive Conditions Using an Acridono-Crown Ether Neutral Ionophore.在竞争条件下使用吖啶酮冠醚中性离子载体快速电位分析水相中铅。
Sensors (Basel). 2018 May 3;18(5):1407. doi: 10.3390/s18051407.
4
Synthesis and pK determination of new enantiopure dimethyl-substituted acridino-crown ethers containing a carboxyl group: Useful candidates for enantiomeric recognition studies.含羧基的新型对映体纯二甲基取代吖啶并冠醚的合成与pK测定：对映体识别研究的有用候选物
Chirality. 2017 Sep;29(9):522-535. doi: 10.1002/chir.22721. Epub 2017 Jun 26.
5
Stimuli-responsive host-guest systems based on the recognition of cryptands by organic guests.基于有机客体对穴醚的识别的刺激响应主体-客体体系。
Acc Chem Res. 2014 Jul 15;47(7):1995-2005. doi: 10.1021/ar500046r. Epub 2014 May 8.
6
Iptycene-derived crown ether hosts for molecular recognition and self-assembly.基于薁衍生的冠醚主体用于分子识别和自组装。
Acc Chem Res. 2014 Jul 15;47(7):2026-40. doi: 10.1021/ar5000677. Epub 2014 May 30.
7
Acridino-Diaza-20-Crown-6 Ethers: New Macrocyclic Hosts for Optochemical Metal Ion Sensing.氮杂Diaza-20-冠-6 醚：用于光化学金属离子传感的新型大环主体。
Molecules. 2021 Jul 1;26(13):4043. doi: 10.3390/molecules26134043.
8
High affinity crown ether complexes in water: thermodynamic analysis, evidence of crystallography and binding of NAD+.高亲和冠醚配合物在水中：热力学分析、晶体学证据和 NAD+的结合。
J Org Chem. 2012 Nov 2;77(21):9766-73. doi: 10.1021/jo301911w. Epub 2012 Oct 17.
9
Response of a benzoxainone derivative linked to monoaza-15-crown-5 with divalent heavy metals.与单氮杂-15-冠-5相连的苯并恶嗪酮衍生物对二价重金属的响应
Talanta. 1998 Aug;46(4):573-81. doi: 10.1016/s0039-9140(97)00319-6.
10
Supramolecular Gel Based on Crown-Ether-Appended Dynamic Covalent Macrocycles.基于冠醚修饰的动态共价大环的超分子凝胶。
Macromol Rapid Commun. 2019 Sep;40(17):e1800731. doi: 10.1002/marc.201800731. Epub 2019 Jan 23.

本文引用的文献

1
Reusable Glucose-Based Crown Ethers Anchored to PVC.固定于聚氯乙烯的可重复使用的基于葡萄糖的冠醚。
Molecules. 2023 Dec 2;28(23):7905. doi: 10.3390/molecules28237905.
2
Grafting of Crown Ether and Cryptand Macrocycles on Large Pore Stellate Mesoporous Silica for Sodium Cation Extraction.冠醚和cryptand 大环在大孔星状介孔硅上的接枝用于钠离子萃取。
Molecules. 2023 Jun 7;28(12):4622. doi: 10.3390/molecules28124622.
3
Synthesis of multifunctional crown ether covalent organic nanospheres as stationary phase for capillary electrochromatography.
多功能冠醚共价有机纳米球的合成及其作为毛细管电色谱固定相的应用。
J Chromatogr A. 2022 Aug 16;1677:463323. doi: 10.1016/j.chroma.2022.463323. Epub 2022 Jul 9.
4
Direct synthetic routes to functionalised crown ethers.通往官能化冠醚的直接合成路线。
Org Chem Front. 2021 Jul 1;8(19):5531-5549. doi: 10.1039/d1qo00699a. eCollection 2021 Sep 28.
5
Separation of Inorganic Anions Using an 18-Crown-6-ether-modified Organic Polymer Monolithic Stationary Phase in Capillary Ion Chromatography.用 18-冠-6-醚修饰的有机聚合物整体柱固定相在毛细管离子色谱中分离无机阴离子。
Anal Sci. 2021 Jun 10;37(6):845-850. doi: 10.2116/analsci.20P279. Epub 2020 Oct 9.
6
Platinum (IV) Recovery from Waste Solutions by Adsorption onto Dibenzo-30-crown-10 Ether Immobilized on Amberlite XAD7 Resin-Factorial Design Analysis.用二苯并-30-冠-10 醚固载在 Amberlite XAD7 树脂上吸附从废溶液中回收铂（IV）-析因设计分析。
Molecules. 2020 Aug 13;25(16):3692. doi: 10.3390/molecules25163692.
7
Efficient diastereoselective synthesis of a new class of azanucleosides: 2'-homoazanucleosides.一类新型氮杂核苷：2'-高氮杂核苷的高效非对映选择性合成。
Tetrahedron. 2017 Jul 27;73(30):4307-4316. doi: 10.1016/j.tet.2017.05.083. Epub 2017 May 29.
8
Fast Potentiometric Analysis of Lead in Aqueous Medium under Competitive Conditions Using an Acridono-Crown Ether Neutral Ionophore.在竞争条件下使用吖啶酮冠醚中性离子载体快速电位分析水相中铅。
Sensors (Basel). 2018 May 3;18(5):1407. doi: 10.3390/s18051407.
9
Synthesis of a library of propargylated and PEGylated α-hydroxy acids toward "clickable" polylactides via hydrolysis of cyanohydrin derivatives.通过氰醇衍生物水解合成炔丙基化和聚乙二醇化α-羟基酸文库以制备“可点击”聚丙交酯
J Org Chem. 2014 Oct 17;79(20):9546-55. doi: 10.1021/jo5016135. Epub 2014 Oct 6.
10
Lead(II) ion selective electrodes with PVC membranes based on two bis-thioureas as ionophores: 1,3-bis(N'-benzoylthioureido)benzene and 1,3-bis(N'-furoylthioureido)benzene.基于两种双硫脲作为离子载体的 PVC 膜铅(II)离子选择电极：1,3-双（N'-苯甲酰硫脲基）苯和 1,3-双（N'-呋喃甲酰硫脲基）苯。
J Hazard Mater. 2010 Sep 15;181(1-3):140-6. doi: 10.1016/j.jhazmat.2010.04.107. Epub 2010 May 2.