Azhari Rad Reyhaneh, Naghdi Yasaman, Majidi Jamalabadi Mobina, Masoumi Sima, Rezakhani Leila, Alizadeh Morteza
Student Research Committee, School of Paramedicine, Shahroud University of Medical Sciences, Shahroud, Iran.
Student Research Committee, School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, Iran.
Breast Cancer (Auckl). 2024 Mar 11;18:11782234241236358. doi: 10.1177/11782234241236358. eCollection 2024.
Despite recent improvements in detecting and managing breast cancer (BC), it continues to be a major worldwide health concern that annually affects millions of people. Exploring the anti-BC potentials of natural compounds has received a lot of scientific attention due to their multi-target mode of action and good safety profiles because of these unmet needs. Drugs made from herbs are secure and have a lot fewer negative effects than those made from synthetic materials. Early stage patients benefit from breast-conserving surgery, but the risk of local recurrence remains, necessitating implanted scaffolds. These scaffolds provide residual cancer cell killing and tailored drug delivery. This review looks at plant extract-infused tissue engineering scaffolds, which provide a novel approach to treating BC. By offering patient individualized, safer treatments, these scaffolds could completely change how BC is treated.
尽管近年来在乳腺癌（BC）的检测和管理方面有所改善，但它仍然是一个全球主要的健康问题，每年影响数百万人。由于天然化合物的多靶点作用模式以及鉴于这些未满足的需求所具有的良好安全性，探索其抗乳腺癌潜力受到了很多科学关注。草药制成的药物安全，且副作用比合成材料制成的药物少得多。早期患者受益于保乳手术，但局部复发风险仍然存在，因此需要植入支架。这些支架可实现残留癌细胞杀伤和定制化药物递送。本综述着眼于注入植物提取物的组织工程支架，其为治疗乳腺癌提供了一种新方法。通过提供针对患者个体的更安全治疗，这些支架可能会彻底改变乳腺癌的治疗方式。
