Tkak Hassnae, Sara Anane, Hamami Amal, Elouali Aziza, Babakhouya Abdeladim, Rkain Maria
Department of Pediatrics, University Hospital Mohamed VI, Faculty of Medicine and Pharmacy, University Mohamed First, Oujda, MAR.
Department of Pediatrics, University Hospital Mohamed VI, Faculty of Medicine and Pharmacy, University Mohamed First,, Oujda, MAR.
Cureus. 2024 Feb 11;16(2):e54003. doi: 10.7759/cureus.54003. eCollection 2024 Feb.
Systemic lupus erythematosus (SLE) is a rare disease in children but is more severe than in adults. SLE may be associated with various non-specific hepatic manifestations, but subacute lupus hepatitis remains unusual and is rarely a mode of revelation. Diagnosis is based on a combination of clinical, laboratory, and histological findings after ruling out other causes of hepatitis, notably autoimmune hepatitis (AIH). We report the case of a young girl with undiagnosed SLE, which first revealed itself as liver involvement and progressed well on corticosteroid therapy. During the course of her illness, she presented with other manifestations that led us to think of SLE with lupus hepatitis.
系统性红斑狼疮（SLE）在儿童中是一种罕见疾病，但比成人更为严重。SLE可能与各种非特异性肝脏表现相关，但亚急性狼疮性肝炎仍然不常见，很少作为首发表现。诊断基于排除其他肝炎病因（尤其是自身免疫性肝炎[AIH]）后的临床、实验室和组织学检查结果。我们报告了一例未确诊的SLE年轻女孩病例，该病最初表现为肝脏受累，经皮质类固醇治疗后病情进展良好。在她的病程中，出现了其他表现，使我们考虑为伴有狼疮性肝炎的SLE。
