School of Medicine and Dentistry, Griffith University, Queensland, Australia.
School of Population Health, University of New South Wales, New South Wales, Australia.
Fam Pract. 2024 Oct 8;41(5):680-692. doi: 10.1093/fampra/cmae015.
Primary care clinicians have key responsibilities in obesity prevention and weight management.
We aimed to identify risk factors for developing obesity among people aged ≥45 years.
We conducted a record linkage longitudinal study of residents of metropolitan Sydney, Australia using data from the: (1) 45 and Up Study at baseline (2005-2009) and first follow-up (2012-2015); (2) Medicare claims; (3) Pharmaceutical Benefits Scheme; and (4) deaths registry. We examined risk factors for developing obesity (body mass index [BMI]: 30-40) at follow-up, separately for people within the: (1) healthy weight range (BMI 18.5-<25) and (2) overweight range (BMI 25-<30) at baseline. Covariates included demographics, modifiable behaviours, health status, allied health use, and medication use. Crude and adjusted relative risks were estimated using Poisson regression modelling.
At follow-up, 1.1% (180/16,205) of those in the healthy weight range group, and 12.7% (1,939/15,266) of those in the overweight range group developed obesity. In both groups, the following were associated with developing obesity: current smoking at baseline, physical functioning limitations, and allied health service use through team care planning, while any alcohol consumption and adequate physical activity were found to be associated with a lower risk of developing obesity. In the healthy weight group, high psychological distress and the use of antiepileptics were associated with developing obesity. In the overweight group, female sex and full-time work were associated with developing obesity, while older age was found to be associated with a lower risk of developing obesity.
These findings may inform the targeting of preventive interventions for obesity in clinical practice and broader public health programs.
初级保健临床医生在肥胖预防和体重管理方面承担着关键责任。
我们旨在确定≥45 岁人群中肥胖发展的危险因素。
我们对澳大利亚大都市悉尼的居民进行了一项基于记录的纵向研究,使用了以下数据来源:(1)45 岁及以上研究的基线(2005-2009 年)和第一次随访(2012-2015 年);(2)医疗保险索赔;(3)药品福利计划;(4)死亡登记处。我们分别检查了在随访时发展为肥胖(体重指数 [BMI]:30-40)的风险因素,针对基线时处于:(1)健康体重范围(BMI 18.5-<25)和(2)超重范围(BMI 25-<30)的人群。协变量包括人口统计学、可改变的行为、健康状况、辅助医疗保健使用和药物使用。使用泊松回归模型估计了粗相对风险和调整相对风险。
在随访时,健康体重组中 1.1%(180/16205)和超重组中 12.7%(1939/15266)的人发展为肥胖。在这两个组中,以下因素与肥胖的发展相关:基线时的当前吸烟、身体功能受限以及通过团队护理计划使用辅助医疗保健服务,而任何饮酒和充足的体育活动与肥胖发展的风险降低相关。在健康体重组中,较高的心理困扰和使用抗癫痫药物与肥胖的发展相关。在超重组中,女性和全职工作与肥胖的发展相关,而年龄较大与肥胖发展的风险降低相关。
这些发现可能为临床实践和更广泛的公共卫生计划中的肥胖预防干预措施的目标定位提供信息。