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中国老年人睡眠时长与心血管代谢多重疾病之间的剂量反应关系:一项全国性调查。

Dose-response relationship between sleep duration and cardiovascular metabolic multimorbidity among older adults in China: A nationwide survey.

作者信息

Zhao Yu, Liu Juan, Xia Jing-Hua, Li Cui, Ma Xiu-Qin

机构信息

HanZhong Central Hospital, HanZhong, China.

HanZhong Central Hospital, HanZhong, China.

出版信息

J Affect Disord. 2024 Jun 1;354:75-81. doi: 10.1016/j.jad.2024.03.051. Epub 2024 Mar 11.

Abstract

AIMS AND OBJECTIVES

The purpose of this study was to explore the relationship between the duration of sleep per day and cardiovascular metabolic multimorbidity (CMM) in older adults and to identify how many hours of sleep per day can lead to a lower risk of CMM in older adults.

BACKGROUND

CMM are a common syndrome in the older adults. There may be an association between sleep duration and CMM in older adults, with both insomnia and sleep deprivation having an impact on the health of older adults. Therefore, it is important to explore the possibility that older adults who sleep for a few hours per day may have a lower prevalence of CMM.

METHODS

The study included 9710 older adults. The sleep duration in this study was assessed by the question "How many hours of sleep do you currently get in a day? ". Older adults were defined as having CMM when they had two or more of the five categories of hypertension, diabetes, heart disease, stroke or cardiovascular disease, dyslipidemia. We used multivariate logistic regression analysis to explore the association among sleep duration and CMM. Restrictive cubic splines were used to examine the shape of the association among sleep duration and the CMM. The STROBE checklist was used for this cross-sectional study.

RESULTS

The mean age was 84.78 ± 11.73 years, with 55.5 % being female. Of the total sample, 21.3 % were CMM. When all covariates were adjusted, there was dose-response relationship between sleep duration and CMM. The dose-response relationship between CMM and sleep duration showed that older adults had a lower risk of cardiovascular and metabolic multimorbidity when they slept 9 h and 10 h per day.

CONCLUSION

With the increasing population of older adults, the number of older adults suffering from CMM continues to rise, and adequate sleep time can effectively prevent the occurrence of CMM. We should pay attention to the sleep problem of the older adults.

RELEVANCE TO CLINICAL PRACTICE

This study provided information for healthcare providers to identify circumstances that increase cardiovascular metabolic multimorbidity and suggest the appropriate sleep duration per day to reduce the risk of disease in older adults.

PATIENT OR PUBLIC CONTRIBUTION

Because of the public database data used in this study, all data were collected by survey agency personnel, so this section is not applicable to this study.

摘要

目的与目标

本研究旨在探讨老年人每日睡眠时间与心血管代谢多重疾病(CMM)之间的关系,并确定每日睡多少小时可降低老年人患CMM的风险。

背景

CMM是老年人中的常见综合征。老年人的睡眠时间与CMM之间可能存在关联,失眠和睡眠剥夺均会对老年人的健康产生影响。因此,探讨每日睡眠数小时的老年人CMM患病率可能较低的可能性很重要。

方法

该研究纳入了9710名老年人。本研究中的睡眠时间通过“您目前每天睡多少小时?”这一问题进行评估。当老年人患有高血压、糖尿病、心脏病、中风或心血管疾病、血脂异常这五类中的两种或更多种时,被定义为患有CMM。我们使用多变量逻辑回归分析来探讨睡眠时间与CMM之间的关联。使用限制性立方样条来检验睡眠时间与CMM之间关联的形状。本横断面研究使用了STROBE清单。

结果

平均年龄为84.78±11.73岁,女性占55.5%。在总样本中,21.3%患有CMM。当对所有协变量进行调整后,睡眠时间与CMM之间存在剂量反应关系。CMM与睡眠时间之间的剂量反应关系表明,老年人每日睡9小时和10小时时患心血管和代谢多重疾病的风险较低。

结论

随着老年人口的增加,患CMM的老年人数量持续上升,充足的睡眠时间可有效预防CMM的发生。我们应关注老年人的睡眠问题。

与临床实践的相关性

本研究为医疗保健提供者提供了信息,以识别增加心血管代谢多重疾病的情况,并建议每日适当的睡眠时间以降低老年人的疾病风险。

患者或公众贡献

由于本研究使用的是公共数据库数据,所有数据均由调查机构人员收集,因此本节不适用于本研究。

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