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创伤评分指数在年龄、格拉斯哥昏迷量表、呼吸频率和收缩压评分(TRIAGES)预测孤立性创伤性脑损伤老年患者短期死亡率中的价值:一项回顾性队列研究。

Predictive value of the Trauma Rating Index in Age, Glasgow Coma Scale, Respiratory rate and Systolic blood pressure score (TRIAGES) for the short-term mortality of older patients with isolated traumatic brain injury: a retrospective cohort study.

机构信息

Department of Emergency Medicine, Affiliated Hospital of Nantong University, Nantong, China.

Department of Emergency Medicine, Affiliated Hospital of Nantong University, Nantong, China

出版信息

BMJ Open. 2024 Mar 12;14(3):e082770. doi: 10.1136/bmjopen-2023-082770.

Abstract

OBJECTIVES

This study aimed to evaluate the effectiveness of the Trauma Rating Index in Age, Glasgow Coma Scale, Respiratory rate and Systolic blood pressure score (TRIAGES) in predicting 24-hour in-hospital mortality among patients aged 65 years and older with isolated traumatic brain injury (TBI).

DESIGN

A retrospective, single-centre cohort study.

SETTING

This study was conducted at a government-run tertiary comprehensive hospital.

PARTICIPANTS

This study included 982 patients aged 65 years or older with isolated TBI, who were admitted to the emergency department between 1 January 2020 and 31 December 2021.

INTERVENTIONS

None.

PRIMARY OUTCOME

24-hour in-hospital mortality was the primary outcome.

RESULTS

Among the 982 patients, 8.75% died within 24 hours of admission. The non-survivors typically had higher TRIAGES and lower GCS scores. Logistic regression showed significant associations of both TRIAGES and GCS with mortality; the adjusted ORs were 1.98 (95% CI 1.74 to 2.25) for TRIAGES and 0.72 (95% CI 0.68 to 0.77) for GCS. Receiver operating characteristic (ROC) analysis indicated an area under the ROC curve of 0.86 for GCS and 0.88 for TRIAGES, with a significant difference (p=0.012). However, precision-recall curve (PRC) analysis revealed an area under the PRC of 0.38 for GCS and 0.47 for TRIAGES, without a significant difference (p=0.107).

CONCLUSIONS

The TRIAGES system is a promising tool for predicting 24-hour in-hospital mortality in older patients with TBI, demonstrating comparable or slightly superior efficacy to the GCS. Further multicentre studies are recommended for validation.

摘要

目的

本研究旨在评估创伤评分指数年龄、格拉斯哥昏迷量表、呼吸频率和收缩压评分(TRIAGES)在预测 65 岁及以上合并单纯性颅脑损伤(TBI)患者 24 小时院内死亡率方面的有效性。

设计

回顾性、单中心队列研究。

地点

本研究在一家政府运营的三级综合医院进行。

参与者

本研究纳入 2020 年 1 月 1 日至 2021 年 12 月 31 日期间因单纯性 TBI 入住急诊科的 982 例 65 岁及以上患者。

干预措施

无。

主要结局

24 小时院内死亡率为主要结局。

结果

在 982 例患者中,8.75%的患者在入院后 24 小时内死亡。非幸存者的 TRIAGES 评分通常较高,GCS 评分较低。Logistic 回归显示,TRIAGES 和 GCS 均与死亡率显著相关;TRIAGES 的调整后 OR 为 1.98(95%CI 1.74 至 2.25),GCS 的调整后 OR 为 0.72(95%CI 0.68 至 0.77)。ROC 分析表明 GCS 的 ROC 曲线下面积为 0.86,TRIAGES 的 ROC 曲线下面积为 0.88,差异有统计学意义(p=0.012)。然而,PRC 分析显示 GCS 的 PRC 曲线下面积为 0.38,TRIAGES 的 PRC 曲线下面积为 0.47,差异无统计学意义(p=0.107)。

结论

TRIAGES 系统是预测老年 TBI 患者 24 小时院内死亡率的一种有前途的工具,其预测效果与 GCS 相当或略优。建议开展多中心研究进一步验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5e5/10936470/460ba7e0ba49/bmjopen-2023-082770f01.jpg

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