El Azime Zineb, Handa Samira, Bourkadi Ghita, Aynaou Hayat, Salhi Houda, El Ouahabi Hanan
Department of Endocrinology, Diabetology and Nutrition, Hassan II University Hospital, Fez, Morocco.
Epidemiology and Health Sciences Research Laboratory, Fez, Morocco.
Case Rep Endocrinol. 2024 Mar 6;2024:3865608. doi: 10.1155/2024/3865608. eCollection 2024.
Thyroid tuberculosis is a rare form of extrapulmonary tuberculosis, even in endemic countries such as Morocco; its precise incidence is not well-defined. The clinical presentation of thyroid tuberculosis can vary, often being asymptomatic. Consequently, the diagnosis may be overlooked or delayed. Intriguingly, thyroid tuberculosis can manifest alongside thyrotoxicosis due to Graves' disease, an exceptional association. This article reports a distinctive case of thyroid tuberculosis coexisting with Graves' disease, one of the autoimmune thyroid diseases. A 33-year-old female presented symptoms consistent with hyperthyroidism and bilateral exophthalmos. She was subsequently diagnosed with Graves' disease. Despite initially managed medically, recurrences of the disease led to definitive treatment by total thyroidectomy. Histopathological examination revealed concurrent presence of thyroid tuberculosis.
甲状腺结核是肺外结核的一种罕见形式,即使在摩洛哥等结核病流行国家也是如此;其确切发病率尚不明确。甲状腺结核的临床表现可能多种多样,常常没有症状。因此,诊断可能被忽视或延误。有趣的是,甲状腺结核可能与格雷夫斯病导致的甲状腺毒症同时出现,这是一种特殊的关联。本文报告了一例甲状腺结核与自身免疫性甲状腺疾病之一的格雷夫斯病并存的独特病例。一名33岁女性出现了与甲状腺功能亢进和双侧突眼相符的症状。她随后被诊断为格雷夫斯病。尽管最初进行了药物治疗,但疾病复发导致最终通过全甲状腺切除术进行治疗。组织病理学检查显示同时存在甲状腺结核。