Kataria Sant Parkash, Tanwar Parul, Singh Sneh, Kumar Sanjay
Department of Pathology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana- 124001, India.
Asian Pac J Trop Biomed. 2012 Oct;2(10):839-40. doi: 10.1016/S2221-1691(12)60240-8.
Tuberculosis of the thyroid gland is an uncommon disease and primary involvement of thyroid is even more rare. It is a rare disease even in countries in which tuberculosis is endemic. The diagnosis is often difficult as the clinical presentation has no distinct characteristics. Clinical course of the disease may resemble toxic goiter or acute thyroiditis or may follow a subacute or chronic growth pattern without specific symptomatology. Histologically presence of necrotizing epithelioid cell granulomas along with langhans type giant cells are the hallmark of thyroid tuberculosis. Demonstration of acid fast bacilli by ZN staining confirms the diagnosis, but this stain is frequently negative in tissue sections.
甲状腺结核是一种罕见疾病，甲状腺原发性受累更为罕见。即使在结核病流行的国家，它也是一种罕见疾病。由于临床表现没有明显特征，诊断往往很困难。该疾病的临床过程可能类似于毒性甲状腺肿或急性甲状腺炎，或者可能呈现亚急性或慢性生长模式且无特定症状。组织学上，坏死性上皮样细胞肉芽肿以及朗汉斯型巨细胞的存在是甲状腺结核的标志。通过抗酸染色显示抗酸杆菌可确诊，但在组织切片中这种染色常常呈阴性。
