Boonpucknavig S, Vuttiviroj O, Bunnag C, Bhamarapravati N, Nimmanitya S
Am J Trop Med Hyg. 1979 Sep;28(5):881-4.
By the direct immunofluorescent technic, dengue antigen, human immunoglobulins, and beta 1C globulin were detectable on the surfaces of platelet suspensions from 48% of patients with dengue hemorrhagic fever. The percentages of positive-staining platelets were not related to the severity of thrombocytopenia, which was marked on the day after the patient developed shock or subsidence of fever. It is suggested that an immunologic mechanism is one of the factors associated with the thrombocytopenia caused by increased platelet destruction.
通过直接免疫荧光技术，在48%的登革出血热患者的血小板悬液表面可检测到登革热抗原、人免疫球蛋白和β1C球蛋白。血小板阳性染色的百分比与血小板减少症的严重程度无关，血小板减少症在患者出现休克或热退后最为明显。提示免疫机制是与血小板破坏增加所致血小板减少症相关的因素之一。
