Deibel A, Müllhaupt B
Klinik für Gastroenterologie und Hepatologie, Swiss HPB und Transplantationszentrum, Universitätsspital Zürich und Universität Zürich, Rämistrasse 100, 8091, Zürich, Schweiz.
Inn Med (Heidelb). 2024 Apr;65(4):318-324. doi: 10.1007/s00108-024-01678-3. Epub 2024 Mar 14.
Non-viral infections of the liver are rare to very rare compared to viral infections. They can be caused by various bacteria, helminths, protozoa, and fungi, often leading to liver involvement during dissemination. Some of these infections affect in particular immunocompromised individuals, while others need to be considered in the differential diagnostic work-up in patients returning from tropical countries. In cases where the infection occurs through oral ingestion of eggs, such as in cystic and alveolar echinococcosis, the liver is often the most commonly affected organ. Due to the diversity of non-viral liver infections and their varied clinical manifestations, a comprehensive discussion of all potential pathogens and their effects is not within the scope of this article. Therefore, only a few of these conditions will be discussed in more detail.
与病毒感染相比,肝脏的非病毒感染极为罕见。它们可由各种细菌、蠕虫、原生动物和真菌引起,在播散过程中常导致肝脏受累。其中一些感染尤其影响免疫功能低下的个体,而另一些感染则需要在来自热带国家的患者的鉴别诊断检查中加以考虑。在通过口服虫卵发生感染的情况下,如在囊型和泡型棘球蚴病中,肝脏往往是最常受累的器官。由于非病毒肝脏感染的多样性及其临床表现各异,本文不打算全面讨论所有潜在病原体及其影响。因此,仅对其中少数情况进行更详细的讨论。