Klaschik E, Köppen R, Kämmerer H, Simons F, Bonhoeffer K
Anaesthesist. 1979 Jul;28(7):328-33.
We measured in 8 experimental studies the oxygen and carbon dioxide partial pressure in systemic arterial, mixed venous and wedge-blood. The results were: 1. In healthy mongrel dogs with controlled intermittent and continuous positive pressure ventilation (FIO2 0,21 and 1,0) paO2 greater than pwO2 greater than pvO2 and pwCO2 less than paCO2 less than pvCO2. 2. During experimentally produced left-sided atelectasis of the lung and positioning of the catheter in the pulmonary artery a) in the ventilated lung we found pwO2 greater than paO2 greater than pvO2 and pwCO2 less than paCO2 less than pvCO2 b) in the atelectatic lung we found paO2 greater than pwO2 greater than pvO2 and paCO2 less than pwCO2 less than pvCO2. According to these findings the sample of highly saturated mixed venous blood from a catheter in the pulmonary artery should be a hint that pulmonary capillary blood is mixed with central venous blood.
我们在8项实验研究中测量了体循环动脉血、混合静脉血和楔压血中的氧分压和二氧化碳分压。结果如下:1. 在采用控制性间歇性和持续性正压通气(吸入氧分数为0.21和1.0)的健康杂种犬中,动脉血氧分压(paO2)大于楔压血氧分压(pwO2)大于混合静脉血氧分压(pvO2),楔压血二氧化碳分压(pwCO2)小于动脉血二氧化碳分压(paCO2)小于混合静脉血二氧化碳分压(pvCO2)。2. 在实验性造成的左侧肺不张以及将导管置于肺动脉期间,a)在通气的肺中,我们发现pwO2大于paO2大于pvO2,pwCO2小于paCO2小于pvCO2;b)在肺不张的肺中,我们发现paO2大于pwO2大于pvO2,动脉血二氧化碳分压(paCO2)小于楔压血二氧化碳分压(pwCO2)小于混合静脉血二氧化碳分压(pvCO2)。根据这些发现,肺动脉导管采集的高饱和混合静脉血样本应提示肺毛细血管血与中心静脉血混合。