Wang Tao, Wang Yanling, Yao Yushi
Institute of Immunology and Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Institute of Immunology and Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China; Liangzhu Laboratory, Hangzhou, Zhejiang 310023, China; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Hangzhou, Zhejiang 310003, China.
Cell Host Microbe. 2024 Mar 13;32(3):296-298. doi: 10.1016/j.chom.2024.02.007.
The intestinal microbiota is associated with defense against respiratory viral infections. In this issue of Cell Host & Microbe, Ngo and colleagues show that intestinal commensal segmented filamentous bacteria reprogram alveolar macrophages with improved influenza-viral-neutralizing and phagocytic functions while maintaining inflammatory anergy to better protect the lung.
肠道微生物群与抵御呼吸道病毒感染有关。在本期《细胞宿主与微生物》杂志中，Ngo及其同事表明，肠道共生的分节丝状菌可对肺泡巨噬细胞进行重编程，增强其流感病毒中和及吞噬功能，同时维持炎症无反应状态，从而更好地保护肺部。
