Kim Min-Ku, Yun So-Yeon, Lee Seonkyung, Lee Ja-Ok, Sung Soo-Yun, Lee Ju-Young, Kim Hyo-Jung, Park Hye Youn, Choi Jeong-Yoon, Song Jae-Jin, Choi Byung Yoon, Koo Ja-Won, Kim Ji-Soo
Department of Neurology, Dizziness Center, Clinical Neuroscience Center, Seoul National University Bundang Hospital, Seongnam-si, Republic of Korea.
Biomedical Research Institute, Seoul National University Bundang Hospital, Seongnam-si, Republic of Korea.
Front Neurol. 2024 Feb 29;15:1329418. doi: 10.3389/fneur.2024.1329418. eCollection 2024.
Customized vestibular rehabilitation improved dizziness and imbalance in several randomized controlled trials. In the present study, we determined the efficacy of customized vestibular rehabilitation using real-world observational data.
In this retrospective observational study, we recruited 64 patients (median age = 60, interquartile range = 48-66.3) who completed the customized vestibular rehabilitation from January to December 2022. The outcomes of rehabilitation were evaluated using the dizziness handicap inventory (DHI) or vestibular disorders activities of daily living scale (VADL). The factors associated with outcomes were assessed with a generalized linear model, of which covariates included patients' age, sex, duration of illness, type of vestibular disorders, initial DHI and VADL scores, exercise compliance, and initial hospital anxiety and depression scale (HADS) scores.
After the median of 6 (4-6) weeks of rehabilitation, DHI and VADL scores significantly improved in patients with either peripheral or central vestibular disorders (Wilcoxon signed-rank test, < 0.05). The initial DHI and VADL scores showed a positive while the sum of HADS scores showed a negative correlation with the outcome. In contrast, the age, sex, duration of illness, types of vestibular disorders, and exercise compliance did not affect the outcome.
Customized vestibular rehabilitation is effective for central as well as peripheral disorders, especially when the symptoms are severe and the psychological distress is mild.
在多项随机对照试验中，定制化前庭康复改善了头晕和平衡问题。在本研究中，我们使用真实世界观察数据确定了定制化前庭康复的疗效。
在这项回顾性观察研究中，我们招募了64例于2022年1月至12月完成定制化前庭康复的患者（中位年龄 = 60岁，四分位间距 = 48 - 66.3岁）。使用头晕残障量表（DHI）或前庭疾病日常生活活动量表（VADL）评估康复结果。采用广义线性模型评估与结果相关的因素，其中协变量包括患者的年龄、性别、病程、前庭疾病类型、初始DHI和VADL评分、运动依从性以及初始医院焦虑抑郁量表（HADS）评分。
经过中位时间为6（4 - 6）周的康复后，外周或中枢前庭疾病患者的DHI和VADL评分均显著改善（Wilcoxon符号秩检验，< 0.05）。初始DHI和VADL评分与结果呈正相关，而HADS评分总和与结果呈负相关。相比之下，年龄、性别、病程、前庭疾病类型和运动依从性并不影响结果。
定制化前庭康复对中枢和外周疾病均有效，尤其是在症状严重且心理困扰较轻的情况下。
