Department of Nutrition, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia.
Food Health Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Int J Environ Health Res. 2024 Nov;34(11):3820-3835. doi: 10.1080/09603123.2024.2327522. Epub 2024 Mar 15.
Pesticide residues were extracted using the QuEChERS method, followed by detection by ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). The non-carcinogenic health risk in adult and child consumers was calculated by target hazard quotient (THQ) and total target hazard quotient (TTHQ) in the Monte Carlo Simulation (MCS) method. The rank order of pesticides detected by UHPLC-MS/MS based on median concentration in onion was tebuconazole (0.004551 mg/kg) > imidacloprid (0.00233 mg/kg) > boscalid (0.00211 mg/kg) > diazinon (0.00079 mg/kg) > thiabendazole (0.00075 mg/kg) > acetamiprid (0.00052 mg/kg) > thiophanate-methyl (0.00052 mg/kg) > dichlorvos (0.000349 mg/kg) > fenitrothion (0.000132 mg/kg) > penconazole (0.00005 mg/kg). The median of TTHQ in adults and children's consumers were 4.00E-3 and 2.00E-2, respectively. TTHQ in adults and children's consumers was lower than 1 value. Hence, consumers were in the acceptable range (TTHQ <1). Consequently, onion consumption cannot endanger consumers' health status due to the pesticide residues.
采用 QuEChERS 方法提取农药残留，然后通过超高效液相色谱-串联质谱法（UHPLC-MS/MS）进行检测。利用蒙特卡罗模拟（MCS）方法中的目标危害系数（THQ）和总目标危害系数（TTHQ），计算成人和儿童消费者的非致癌健康风险。基于洋葱中农药残留浓度中位数的 UHPLC-MS/MS 检测到的农药排名顺序为：戊唑醇（0.004551mg/kg）>吡虫啉（0.00233mg/kg）>咯菌腈（0.00211mg/kg）>敌百虫（0.00079mg/kg）>噻菌灵（0.00075mg/kg）>乙虫脒（0.00052mg/kg）>噻虫嗪（0.00052mg/kg）>敌敌畏（0.000349mg/kg）>三唑磷（0.000132mg/kg）>丙环唑（0.00005mg/kg）。成人和儿童消费者的 TTHQ 中位数分别为 4.00E-3和 2.00E-2。成人和儿童消费者的 TTHQ 均低于 1 值。因此，消费者处于可接受范围内（TTHQ<1）。因此，由于农药残留，洋葱的消费不会危害消费者的健康状况。
