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痴呆患者创伤后应激障碍:研究方案。

Posttraumatic stress disorder in people with dementia: study protocol.

机构信息

School for Mental Health and Neuroscience, Department of Psychiatry and Neuropsychology, Maastricht, the Netherlands.

Envida, Care for Older People, Department of Treatment and Support, Maastricht, the Netherlands.

出版信息

Eur J Psychotraumatol. 2024;15(1):2320040. doi: 10.1080/20008066.2024.2320040. Epub 2024 Mar 15.

DOI:10.1080/20008066.2024.2320040
PMID:38488137
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10946268/
Abstract

Posttraumatic stress disorder (PTSD) is considered an independent risk factor for dementia. Despite the (clinical) evidence that PTSD is associated with neuropsychiatric symptoms in people with dementia, studies on its prevalence and clinical manifestation are limited, and their quality is affected by the lack of a structured method to diagnose PTSD in this population. The primary aim of the current study is to validate the 'TRAuma and DEmentia' interview as a diagnostic tool for PTSD in people with dementia and to test feasibility of EMDR treatment for people with PTSD and dementia. This prospective multi-centre study is divided into two parts. In study A, 90 participants with dementia will be included to test the criterion validity, inter-rater reliability and feasibility of the 'TRAuma and DEmentia' interview. In study B, 29 participants with dementia and PTSD will receive eye movement desensitisation and reprocessing therapy by a trained psychologist, and 29 participants with dementia and PTSD will be placed on the waiting list control group. This study aims to improve the diagnostic process of PTSD and to assess the effects of eye movement desensitisation and reprocessing treatment in people with dementia living in Dutch care facilities. NL70479.068.20 / METC 20-063 / OSF registration: https://doi.org/10.17605/OSF.IO/AKW4F.

摘要

创伤后应激障碍(PTSD)被认为是痴呆的独立危险因素。尽管有临床证据表明 PTSD 与痴呆患者的神经精神症状有关,但关于其患病率和临床表现的研究有限,其质量受到缺乏在该人群中诊断 PTSD 的结构化方法的影响。本研究的主要目的是验证“创伤和痴呆”访谈作为痴呆患者 PTSD 的诊断工具,并测试 EMDR 治疗 PTSD 和痴呆患者的可行性。这项前瞻性多中心研究分为两部分。在研究 A 中,将纳入 90 名痴呆症患者,以测试“创伤和痴呆”访谈的标准效度、评分者间信度和可行性。在研究 B 中,29 名痴呆症和 PTSD 患者将由经过培训的心理学家接受眼动脱敏再处理治疗,而 29 名痴呆症和 PTSD 患者将被置于等待名单对照组。本研究旨在改善 PTSD 的诊断过程,并评估眼动脱敏再处理治疗对居住在荷兰护理机构中的痴呆症患者的效果。NL70479.068.20 / METC 20-063 / OSF 注册:https://doi.org/10.17605/OSF.IO/AKW4F。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba5e/10959212/98bf5b10f513/ZEPT_A_2320040_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba5e/10959212/98bf5b10f513/ZEPT_A_2320040_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba5e/10959212/98bf5b10f513/ZEPT_A_2320040_F0001_OC.jpg

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本文引用的文献

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Treatment of post-traumatic stress disorder in people with dementia: a structured literature review.痴呆患者创伤后应激障碍的治疗:系统文献回顾。
Psychogeriatrics. 2023 May;23(3):523-534. doi: 10.1111/psyg.12951. Epub 2023 Mar 17.
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Feasibility of EMDR in Older Adults with PTSD to Reduce Frailty and Improve Quality of Life.眼动脱敏再处理疗法对患有创伤后应激障碍的老年人减轻虚弱并改善生活质量的可行性。
Clin Gerontol. 2025 Jan-Feb;48(1):37-47. doi: 10.1080/07317115.2022.2114397. Epub 2022 Sep 4.
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The Need for a Diagnostic Instrument to Assess Post-Traumatic Stress Disorder in People with Dementia: Findings from a Delphi Study.
需要一种诊断工具来评估痴呆患者的创伤后应激障碍:德尔菲研究的结果。
J Geriatr Psychiatry Neurol. 2023 Mar;36(2):129-142. doi: 10.1177/08919887221103583. Epub 2022 Jun 17.
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A first insight into the clinical manifestation of posttraumatic stress disorder in dementia: a systematic literature review.创伤后应激障碍在痴呆症中的临床表现初探:系统文献回顾。
Psychogeriatrics. 2022 Jul;22(4):509-520. doi: 10.1111/psyg.12830. Epub 2022 Apr 26.
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Comparing Intensive Trauma-Focused Treatment Outcome on PTSD Symptom Severity in Older and Younger Adults.比较针对老年人和年轻人创伤后应激障碍(PTSD)症状严重程度的强化创伤聚焦治疗效果
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Br J Psychiatry. 2021 Mar;218(3):174. doi: 10.1192/bjp.2021.14.
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[The Psychiatric Hospitals (Compulsory Admissions) Act ceases to exist; what does this mean for treating physicians and patients?].[《精神病院(强制收治)法》不再施行;这对治疗医师和患者意味着什么?]
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The FAIR guiding principles for data stewardship: fair enough?FAIR 数据管理原则:足够公平吗?
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