The University of Jordan, Amman, Jordan.
King Hussien Cancer Center, Amman, Jordan.
Integr Cancer Ther. 2024 Jan-Dec;23:15347354241239110. doi: 10.1177/15347354241239110.
Chemotherapy-induced nausea and vomiting (CINV) is one of the most prevalent and distressing side effects of chemotherapy among patients with cancer worldwide. Despite continuing advances in antiemetic medicines, nausea and vomiting associated with cancer chemotherapy remain a substantial therapeutic concern for many patients. However, P6 and Auricular acupressure (AA) have been recognized as potential therapy for managing chemotherapy-induced nausea and vomiting.
This study aimed to evaluate the effectiveness of P6 and Auricular acupressure (AA) in reducing chemotherapy-induced nausea and vomiting among patients with cancer. And to explore a prominent and effective evidence-based protocol for implementing acupressure to treat chemotherapy-induced nausea and vomiting.
This systematic review was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Several databases were used to search for eligible studies using specific keywords. Only systematic reviews and clinical trials on acupressure for managing CINV among adults with cancer were included. This review covered articles published in English from 2015 to 2022.
A total of 14 published studies were included in this review study; 10 articles were trial studies, and the other 4 were systematic review and meta-analysis studies. The quality of 10 included clinical trials were assessed using the Effective Public Health Practice Project (EPHPP) Quality Assessment Tool for quantitative studies, the overall result showed that 40% of study rated with moderate quality, no study was rated with low quality, and (60%) studies rated as high-quality study. As well as the quality assessment of all review studies showed that the majority of included systematic reviews and meta-analysis with a low risk of bias and high to moderate power of evidence. In all included studies the acupressure was utilized as a primary complementary intervention for chemotherapy induced nausea and vomiting. The result of this extensive and comprehensive review the P6 and auricular acupressure is an effective complementary therapy in reducing and controlling chemotherapy-induced nausea and vomiting among participants with various types of cancer and receiving various types of chemotherapy.
The successful and effective application of acupressure in managing CINV for certain types of cancer had been supported in previous literature as a safe, affordable, and non-invasive alternative to pharmaceutical medications. However, standardization guidelines regarding the use of acupressure independently or in combination with other pharmacological therapies to address CINV in various cancers require immediate attention.
化疗引起的恶心和呕吐（CINV）是全球癌症患者中最常见和最令人痛苦的化疗副作用之一。尽管止吐药物不断取得进展，但癌症化疗相关的恶心和呕吐仍然是许多患者的重要治疗关注点。然而，内关穴和耳穴按压（AA）已被认为是管理化疗引起的恶心和呕吐的潜在治疗方法。
本研究旨在评估内关穴和耳穴按压（AA）在减轻癌症患者化疗引起的恶心和呕吐中的有效性。并探索一种突出的、有效的循证方案，将按压疗法应用于治疗化疗引起的恶心和呕吐。
本系统评价按照系统评价和荟萃分析的首选报告项目（PRISMA）进行。使用特定的关键词，在几个数据库中搜索符合条件的研究。仅纳入关于成人癌症患者使用按压疗法管理 CINV 的系统评价和临床试验。本综述涵盖了 2015 年至 2022 年期间发表的英文文章。
本综述共纳入 14 项已发表的研究；10 篇为试验研究，其余 4 篇为系统评价和荟萃分析研究。使用有效公共卫生实践项目（EPHPP）定量研究质量评估工具对 10 项纳入的临床试验的质量进行评估，总体结果显示，40%的研究质量为中等，没有低质量研究，（60%）研究质量为高质量研究。并且，所有综述研究的质量评估表明，纳入的大多数系统评价和荟萃分析具有低偏倚风险和高到中等证据效力。在所有纳入的研究中，按压被用作化疗引起的恶心和呕吐的主要补充干预措施。这项广泛而全面的综述结果表明，内关穴和耳穴按压是一种有效的补充疗法，可减少和控制各种类型癌症患者接受各种类型化疗时的化疗引起的恶心和呕吐。
先前的文献支持按压在管理某些类型癌症的 CINV 方面的成功和有效应用，作为药物治疗的安全、经济实惠且非侵入性的替代方法。然而，立即需要关注关于在各种癌症中单独使用或结合其他药物治疗使用按压来解决 CINV 的标准化指南。
