Department of Physiotherapy and Rehabilitation, Faculty of Hamidiye Health Sciences, University of Health Sciences, Istanbul, Turkey.
Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Bezmialem Vakıf University, İstanbul, Turkey.
Neuropediatrics. 2024 Jun;55(3):171-177. doi: 10.1055/a-2288-6383. Epub 2024 Mar 15.
The Pediatric Quality of Life Inventory™ (PedsQL™) Neuromuscular Module (PedsQL™ 3.0 NM) evaluates the health-related quality of life in children who are affected by neuromuscular diseases. This study's aim is to assess the adaptation of the PedsQL™ 3.0 NM Turkish version (PedsQL™ 3.0 NM-TR) for 2- to 4-year-olds in spinal muscular atrophy (SMA).
The procedure of translating the PedsQL™ 3.0 NM into Turkish was conducted in accordance with the translation methodology outlined by the PedsQL™ measurement model. The PedsQL™ 3.0 NM-TR was administered to 54 parents of children with SMA aged 2 to 4 years. The test-retest reliability and intraclass correlation coefficient (ICC) were measured for reliability analysis. Cronbach's α coefficient and item score correlations were calculated for internal consistency. Concurrent construct validity was evaluated by Pearson correlations between the outcomes of the PedsQL™ 4.0 Generic Core Scale (PedsQL™ 4.0 GCS) and the PedsQL™ 3.0 NM.
The PedsQL™ 3.0 NM-TR total score shows excellent reliability. The Cronbach's α values for the PedsQL™ 3.0 NM ranged between 0.871 and 0.906, while those for the PedsQL™ 4.0 GCS ranged between 0.843 and 0.897. Test-retest ICC values for the PedsQL™ 3.0 NM-TR ranged between 0.812 and 0.917, and for the PedsQL™ 4.0 GCS ranged between 0.773 and 0.899. The relationship between the PedsQL™ 3.0 NM-TR and the subscores of the PedsQL™ 4.0 GCS demonstrated a range of correlations from excellent to fair, indicating the interplay between two scales.
This study established the PedsQL™ 3.0 NM-TR as reliable, valid, and feasible for use in children aged 2 to 4 years with SMA.
儿科生活质量量表（PedsQL™）神经肌肉模块（PedsQL™3.0 NM）评估患有神经肌肉疾病的儿童的健康相关生活质量。本研究旨在评估脊髓性肌萎缩症（SMA）2-4 岁儿童使用 PedsQL™3.0 NM 土耳其语版本（PedsQL™3.0 NM-TR）的适用性。
按照 PedsQL™测量模型概述的翻译方法，将 PedsQL™3.0 NM 翻译成土耳其语。对 54 名 2-4 岁 SMA 儿童的家长进行了 PedsQL™3.0 NM-TR 测试。为进行可靠性分析，测量了重测信度和组内相关系数（ICC）。为进行内部一致性分析，计算了 Cronbach's α 系数和项目得分相关性。通过 PedsQL™4.0 通用核心量表（PedsQL™4.0 GCS）和 PedsQL™3.0 NM 结果之间的 Pearson 相关评估同时效性结构效度。
PedsQL™3.0 NM-TR 总分显示出极好的可靠性。PedsQL™3.0 NM 的 Cronbach's α 值在 0.871 到 0.906 之间，而 PedsQL™4.0 GCS 的 Cronbach's α 值在 0.843 到 0.897 之间。PedsQL™3.0 NM-TR 的重测 ICC 值在 0.812 到 0.917 之间，而 PedsQL™4.0 GCS 的重测 ICC 值在 0.773 到 0.899 之间。PedsQL™3.0 NM-TR 与 PedsQL™4.0 GCS 各分量表之间的关系显示出从极好到适度的相关性范围，表明两个量表之间存在相互作用。
本研究确立了 PedsQL™3.0 NM-TR 在用于 2-4 岁 SMA 儿童时具有可靠性、有效性和可行性。
