Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR.
Department of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Health Qual Life Outcomes. 2023 Jan 30;21(1):10. doi: 10.1186/s12955-022-02077-8.
Childhood cancer negatively impacts a child's physical, mental, and behavioural health and significantly affects their health-related quality of life. The Pediatric Quality of Life Inventory 4.0 Generic Core Scale (PedsQL™ 4.0 GCS) is one of the most commonly used measures of the quality of life in children. However, the Amharic version of PedsQL™ 4.0 GCS has not been validated in a paediatric oncology population. This study aimed to translate and evaluate the psychometric properties of the Amharic PedsQL™ 4.0 GCS (PedsQL™ 4.0 GCS (A)) for Ethiopian children with cancer.
A descriptive cross-sectional study was conducted among children aged 8-18 years with any type of cancer across the cancer trajectory. Cronbach's alpha and intraclass correlation coefficient were computed to determine the internal consistency and test-retest reliability of the scale. The convergent validity was established by examining the correlation of the PedsQL™ 4.0 GCS (A) with the Amharic version of the Revised Child Anxiety and Depression Scale (RCADS-25(A)). Factorial validity was evaluated by conducting a confirmatory factor analysis.
The study included 142 participants with childhood cancer. PedsQL™ 4.0 GCS (A) had good validity and reliability. It demonstrated high internal consistency with a Cronbach's alpha of 0.96 for the scale and 0.82-0.95 for the subscales. The intraclass correlation coefficient for the scale was 0.9 and that for the subscales was 0.76-0.90. The PedsQL™ 4.0 GCS (A) was highly correlated with RCADS-25 (A) (r = - 0.97, p < 0.001), supporting its convergent validity. The four-factor structure of the model fitted the data satisfactorily (χ/df = 1.28; CFI = 0.97; TLI = 0.97; RMSEA = 0.05; SRMR = 0.05), supporting the factorial validity of the PedsQL™ 4.0 GCS (A).
The PedsQL™ 4.0 GCS (A) demonstrates desirable psychometric properties for assessing quality of life among Ethiopian children with cancer. The scale can be used in clinical settings for assessing and evaluating quality of life in children with cancer. The use of parent-report versions and studies in those with different health conditions and healthy populations are necessary to further establish the psychometric properties of the PedsQL™ 4.0 GCS (A).
儿童癌症会对儿童的身体、心理和行为健康产生负面影响，显著影响他们的健康相关生活质量。儿科生活质量量表 4.0 通用核心量表（PedsQLTM 4.0 GCS）是衡量儿童生活质量最常用的指标之一。然而，儿科生活质量量表 4.0 通用核心量表（PedsQLTM 4.0 GCS）的阿姆哈拉语版本尚未在儿科肿瘤患者中得到验证。本研究旨在翻译并评估阿姆哈拉语儿科生活质量量表 4.0 通用核心量表（PedsQLTM 4.0 GCS（A））在埃塞俄比亚癌症儿童中的心理测量特性。
这是一项在癌症病程中患有任何类型癌症的 8-18 岁儿童中进行的描述性横断面研究。采用克朗巴赫系数和组内相关系数来确定量表的内部一致性和重测信度。通过考察 PedsQLTM 4.0 GCS（A）与阿姆哈拉语修订儿童焦虑和抑郁量表（RCADS-25（A））的相关性来确定其聚合效度。采用验证性因子分析来评估因子有效性。
该研究纳入了 142 名患有儿童癌症的参与者。PedsQLTM 4.0 GCS（A）具有良好的有效性和可靠性。它具有很高的内部一致性，量表的克朗巴赫系数为 0.96，分量表的克朗巴赫系数为 0.82-0.95。量表的组内相关系数为 0.9，分量表的组内相关系数为 0.76-0.90。PedsQLTM 4.0 GCS（A）与 RCADS-25（A）高度相关（r=-0.97，p<0.001），支持其聚合效度。模型的四因素结构拟合数据令人满意（χ/df=1.28；CFI=0.97；TLI=0.97；RMSEA=0.05；SRMR=0.05），支持 PedsQLTM 4.0 GCS（A）的因子有效性。
阿姆哈拉语儿科生活质量量表 4.0 通用核心量表（PedsQLTM 4.0 GCS（A））在评估埃塞俄比亚癌症儿童生活质量方面具有理想的心理测量特性。该量表可用于临床环境，评估和评估癌症儿童的生活质量。需要使用家长报告版本和在具有不同健康状况和健康人群中的研究来进一步确定 PedsQLTM 4.0 GCS（A）的心理测量特性。
