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接种 SARS-CoV-2 疫苗后 AAV、抗 GBM 病和双阳性患者的临床表型。

Clinical phenotype of AAV, anti-GBM disease and double-positive patients after SARS-CoV-2 vaccination.

机构信息

Department of Nephrology, The First Medical Centre, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center of Kidney Diseases, Beijing, China.

Department of Nephrology, The First Medical Centre, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center of Kidney Diseases, Beijing, China.

出版信息

Autoimmun Rev. 2024 Apr;23(4):103521. doi: 10.1016/j.autrev.2024.103521. Epub 2024 Mar 13.

Abstract

The number of anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV), anti-glomerular basement membrane (GBM) disease and double-positive patients (DPPs) following the coronavirus disease 2019 (COVID-19) vaccine reported in the literature is increasing, we reviewed the reported cases of AAV, anti-GBM disease and DPPs subsequent to COVID-19 vaccination, and compared the disparities in DPPs who received the COVID-19 vaccination and those who did not. We did not observe any differences in clinical phenotype of AAV, anti-GBM disease and DPPs before and after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination.

摘要

文献报道的 COVID-19 疫苗接种后抗中性粒细胞胞浆抗体(ANCA)相关性血管炎(AAV)、抗肾小球基底膜(GBM)疾病和双阳性患者(DPP)的数量正在增加,我们复习了 COVID-19 疫苗接种后报道的 AAV、抗 GBM 疾病和 DPP 病例,并比较了 COVID-19 疫苗接种和未接种 DPP 的差异。我们没有观察到 SARS-CoV-2 疫苗接种前后 AAV、抗 GBM 疾病和 DPP 的临床表型有任何差异。

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