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体外受精后成功的预测因素。

Predictors of success after in vitro fertilization.

机构信息

Aberdeen Centre for Reproductive Medicine, NHS Grampian, Aberdeen, Aberdeenshire, United Kingdom; School of Medicine, Nutrition Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, Aberdeenshire, United Kingdom.

School of Medicine, Nutrition Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, Aberdeenshire, United Kingdom; Aberdeen Maternity Hospital, NHS Grampian and University of Aberdeen, Aberdeen, Aberdeenshire, United Kingdom.

出版信息

Fertil Steril. 2024 May;121(5):742-751. doi: 10.1016/j.fertnstert.2024.03.003. Epub 2024 Mar 16.

Abstract

The last few decades have witnessed a rise in the global uptake of in vitro fertilization (IVF) treatment. To ensure optimal use of this technology, it is important for patients and clinicians to have access to tools that can provide accurate estimates of treatment success and understand the contribution of key clinical and laboratory parameters that influence the chance of conception after IVF treatment. The focus of this review was to identify key predictors of IVF treatment success and assess their impact in terms of live birth rates. We have identified 11 predictors that consistently feature in currently available prediction models, including age, duration of infertility, ethnicity, body mass index, antral follicle count, previous pregnancy history, cause of infertility, sperm parameters, number of oocytes collected, morphology of transferred embryos, and day of embryo transfer.

摘要

在过去的几十年中,全球范围内体外受精(IVF)治疗的采用率有所上升。为了确保这项技术得到最佳利用,患者和临床医生需要能够准确估计治疗成功率的工具,并了解影响 IVF 治疗后受孕机会的关键临床和实验室参数的贡献。本综述的重点是确定 IVF 治疗成功的关键预测因素,并评估它们在活产率方面的影响。我们已经确定了 11 个预测因素,这些因素在目前可用的预测模型中经常出现,包括年龄、不孕持续时间、种族、体重指数、窦卵泡计数、既往妊娠史、不孕原因、精子参数、采集的卵子数量、移植胚胎的形态以及胚胎移植日。

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