迈入真菌组驱动癌症研究的时代。
Into the era of mycobiome-driven cancer research.
机构信息
Department of Thoracic Surgery, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi 214023, Jiangsu, China; Wuxi College of Clinical Medicine, Nanjing Medical University, Wuxi 214023, Jiangsu, China.
State Key Laboratory of Systems Medicine for Cancer, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
出版信息
Trends Cancer. 2024 May;10(5):389-392. doi: 10.1016/j.trecan.2024.02.009. Epub 2024 Mar 16.
The cancer mycobiome has recently become a research hotspot. While the intratumor mycobiota is implicated in cancer initiation and progression, the gut mycobiota functions as biomarkers for cancer diagnosis and treatment. In this forum article we highlight the involvement of the mycobiome in correlation-, causation-, and prediction-oriented cancer research and discuss the potential of this burgeoning field.
癌症真菌组最近成为研究热点。虽然肿瘤内真菌群与癌症的发生和发展有关，但肠道真菌群则作为癌症诊断和治疗的生物标志物。在这篇专题文章中，我们强调了真菌组在相关性、因果性和预测性癌症研究中的作用，并讨论了这个新兴领域的潜力。
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