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NaOH 摄入后急性口腔化学烧伤的有效治疗:一例报告。

Effective Management of Acute Oral Chemical Burns After NaOH Ingestion: A Case Report.

机构信息

Department of Stomatology, Qingbaijiang District People's Hospital, Chengdu, Sichuan, China (mainland).

Department of Gastroenterology, Qingbaijiang District People's Hospital, Chengdu, Sichuan, China (mainland).

出版信息

Am J Case Rep. 2024 Mar 18;25:e943134. doi: 10.12659/AJCR.943134.

DOI:10.12659/AJCR.943134
PMID:38494665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10958186/
Abstract

BACKGROUND Chemical burns in the oral cavity, although rare, cause more severe tissue damage than thermal burns, continuing tissue destruction even after removing the causative substance. Prompt identification of the substance, exposure extent, time from injury to treatment, and the injured area are imperative for effective management. This report details severe oral burns in an elderly woman from accidental NaOH ingestion. CASE REPORT A 70-year-old female patient was presented to our hospital approximately 15 h after inadvertent consumption of approximately 20 ml of NaOH (sodium hydroxide) solution. This incident led to oral discomfort and restricted mouth opening. The ingested solution, erroneously assumed to be a beverage, was later identified as a potent alkaline substance typically employed in grease removal. Initial manifestations included intense burning sensation, oral edema, and heightened salivation, which exacerbated on the following day, adversely impacting her alimentation and verbal communication. Clinical examination disclosed extensive damage to the oral mucosa. The diagnosis encompassed a chemical burn in the oral cavity coupled with chronic gastritis. The treatment regimen comprised dietary limitations, administration of famotidine for gastric acid suppression, intravenous hydration, nutritional support, oral care with Kangfuxin liquid, and nebulization therapy. Six months after therapy, she exhibited complete recovery, with the absence of discomfort and restored normal oral functions. CONCLUSIONS Timely and targeted treatment strategies, particularly nebulization medication and Kangfuxin liquid, are effective in managing chemical burns in the oral cavity, promoting wound healing, and preventing complications.

摘要

背景

口腔化学烧伤虽然罕见,但比热力烧伤造成更严重的组织损伤,即使去除致病物质后仍持续进行组织破坏。迅速识别物质、暴露程度、从受伤到治疗的时间以及受伤区域对于有效管理至关重要。本报告详细介绍了一位老年女性因意外摄入 NaOH 而导致的严重口腔烧伤。

病例报告

一位 70 岁女性患者在误服约 20 毫升 NaOH(氢氧化钠)溶液后约 15 小时被送往我院。这导致口腔不适和张口受限。该溶液被错误地认为是一种饮料,后来被确认为一种常用于去除油脂的强碱物质。最初的表现包括强烈的烧灼感、口腔肿胀和增加的唾液分泌,次日病情加重,影响她的饮食和言语交流。临床检查显示口腔黏膜广泛受损。诊断包括口腔化学烧伤合并慢性胃炎。治疗方案包括饮食限制、法莫替丁抑制胃酸、静脉补液、营养支持、康复新液口腔护理和雾化治疗。治疗 6 个月后,她完全康复,无不适且口腔功能恢复正常。

结论

及时和有针对性的治疗策略,特别是雾化药物和康复新液,对于口腔化学烧伤的治疗有效,可促进伤口愈合并预防并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bb2/10958186/13b79cbecbfb/amjcaserep-25-e943134-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bb2/10958186/8dae349d8157/amjcaserep-25-e943134-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bb2/10958186/13b79cbecbfb/amjcaserep-25-e943134-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bb2/10958186/8dae349d8157/amjcaserep-25-e943134-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bb2/10958186/13b79cbecbfb/amjcaserep-25-e943134-g002.jpg

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