Ma Jiahui, Yang Xue, Liu Zhiming, Fu Hao, Fan Sizhou, Wang Kai, Li Yan, Huang Lvzhen, Zhao Mingwei
Department of Ophthalmology, Peking University People's Hospital, Beijing, People's Republic of China.
Eye Diseases and Optometry Institute, Peking University People's Hospital, Beijing, People's Republic of China.
Clin Ophthalmol. 2024 Mar 12;18:799-807. doi: 10.2147/OPTH.S453731. eCollection 2024.
To investigate the impact of vergence dysfunction on myopia progression in children with Defocus incorporated multiple segments (DIMS) spectacle lenses.
We retrospectively enrolled children prescribed DIMS spectacle lenses to slow myopic progression. Baseline vergence dysfunction was determined according to phoria at distance and near. Axial length (AL) measurement and cycloplegic subjective refraction were performed before fitting the lenses and at six-month and one-year follow-ups. The six-month and one-year AL and spherical equivalent (SE) change from baseline were calculated and compared in subgroups stratified with the type of vergence dysfunction.
Two hundred and ninety-two myopic children were included. Significant AL elongation and SE progression were observed at six months and one year ( < 0.05 for all comparisons). Multiple regression demonstrated that AL elongation at six months ( < 0.001) and one year ( < 0.001) was negatively correlated with age, and SE progression at six months was associated with age ( = 0.002). The AL elongation at six months in children with convergence excess was significantly greater than in normal myopic subjects ( = 0.011) and subjects with convergence insufficiency ( = 0.008), divergence excess ( = 0.007), divergence insufficiency ( = 0.024) and basic esophoria ( = 0.048) at six months.
The present research demonstrated that vergence dysfunction influences myopia progression for myopic children with DIMS, and the children with convergence excess suffer from the greatest myopia progression among different types of vergence dysfunction.
探讨聚散功能异常对使用离焦型多焦点(DIMS)眼镜片的儿童近视进展的影响。
我们回顾性纳入了佩戴DIMS眼镜片以减缓近视进展的儿童。根据远距离和近距离隐斜来确定基线聚散功能异常。在配镜前、随访6个月和1年时进行眼轴长度(AL)测量和散瞳主观验光。计算并比较不同聚散功能异常类型分层的亚组中,6个月和1年时相对于基线的AL和等效球镜度(SE)变化。
纳入292名近视儿童。在6个月和1年时观察到显著的眼轴伸长和SE进展(所有比较均P<0.05)。多元回归显示,6个月(P<0.001)和1年(P<0.001)时的眼轴伸长与年龄呈负相关,6个月时的SE进展与年龄相关(P = 0.002)。6个月时集合过度儿童的眼轴伸长显著大于正常近视儿童(P = 0.011)以及6个月时集合不足(P = 0.008)、散开过度(P = 0.007)、散开不足(P = 0.024)和基本型内隐斜(P = 0.048)的儿童。
本研究表明,聚散功能异常会影响佩戴DIMS眼镜片的近视儿童的近视进展,在不同类型的聚散功能异常中,集合过度的儿童近视进展最为明显。