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细胞膜张力梯度、膜流和细胞过程。

Cell Membrane Tension Gradients, Membrane Flows, and Cellular Processes.

机构信息

Cellular and Molecular Physiology, Yale University, New Haven, Connecticut, United States.

Nanobiology Institute, Yale University, West Haven, Connecticut, United States.

出版信息

Physiology (Bethesda). 2024 Jul 1;39(4):0. doi: 10.1152/physiol.00007.2024. Epub 2024 Mar 19.

DOI:10.1152/physiol.00007.2024
PMID:38501962
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11368524/
Abstract

Cell membrane tension affects and is affected by many fundamental cellular processes, yet it is poorly understood. Recent experiments show that membrane tension can propagate at vastly different speeds in different cell types, reflecting physiological adaptations. Here we briefly review the current knowledge about membrane tension gradients, membrane flows, and their physiological context.

摘要

细胞膜张力会影响许多基本的细胞过程,同时也会受到这些过程的影响,但人们对此知之甚少。最近的实验表明,细胞膜张力在不同的细胞类型中可以以截然不同的速度传播,反映了生理适应性。本文简要回顾了关于细胞膜张力梯度、膜流动及其生理背景的现有知识。

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Cell. 2023 Jul 6;186(14):3049-3061.e15. doi: 10.1016/j.cell.2023.05.014. Epub 2023 Jun 12.
3
Serinc5 Restricts HIV Membrane Fusion by Altering Lipid Order and Heterogeneity in the Viral Membrane.Serinc5 通过改变病毒膜中的脂质有序性和异质性来限制 HIV 膜融合。
ACS Infect Dis. 2023 Apr 14;9(4):773-784. doi: 10.1021/acsinfecdis.2c00478. Epub 2023 Mar 22.
4
Spatial organization of lysosomal exocytosis relies on membrane tension gradients.溶酶体胞吐作用的空间组织依赖于膜张力梯度。
Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2207425120. doi: 10.1073/pnas.2207425120. Epub 2023 Feb 17.
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Fluorescent Flippers: Small-Molecule Probes to Image Membrane Tension in Living Systems.荧光脚蹼:用于活体系统中膜张力成像的小分子探针。
Angew Chem Int Ed Engl. 2023 May 8;62(20):e202217868. doi: 10.1002/anie.202217868. Epub 2023 Feb 23.
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ACS Sens. 2023 Jan 27;8(1):12-18. doi: 10.1021/acssensors.2c01921. Epub 2023 Jan 6.
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