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1
A single dose comparison of piretanide and bumetanide in congestive cardiac failure.匹拉噻米与布美他尼治疗充血性心力衰竭的单剂量比较
Br J Clin Pharmacol. 1979 Aug;8(2):173-8. doi: 10.1111/j.1365-2125.1979.tb05817.x.
2
Effects of piretanide, bumetanide and frusemide on electrolyte and urate excretion in normal subjects.吡咯他尼、布美他尼和呋塞米对正常受试者电解质及尿酸盐排泄的影响。
Br J Clin Pharmacol. 1978 Aug;6(2):129-33. doi: 10.1111/j.1365-2125.1978.tb00837.x.
3
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4
Piretanide, a potent diuretic with potassium-sparing properties, for the treatment of congestive heart failure.吡咯他尼，一种具有保钾特性的强效利尿剂，用于治疗充血性心力衰竭。
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[Clinical comparative trial of piretanide and furosemide in patients with advanced renal insufficiency. Drug levels and diuretic potency of single oral doses].[吡咯他尼与呋塞米治疗晚期肾功能不全患者的临床对比试验。单次口服剂量的药物水平及利尿效能]
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引用本文的文献

1
Assessment of natriuretic drugs.利钠药物的评估。
Br J Clin Pharmacol. 1981 Oct;12(4):465-74. doi: 10.1111/j.1365-2125.1981.tb01252.x.
2
The effects of a combination of piretanide and triamterene in healthy subjects.吡咯他尼与氨苯蝶啶联合用药对健康受试者的影响。
Br J Clin Pharmacol. 1981 Jan;11(1):106-8. doi: 10.1111/j.1365-2125.1981.tb01117.x.
3
Oral piretanide in chronic renal failure.慢性肾衰竭中口服布美他尼的应用
Br J Clin Pharmacol. 1982 Dec;14(6):857-60. doi: 10.1111/j.1365-2125.1982.tb02049.x.
4
Acute haemodynamic effects of a single intravenous dose of piretanide in congestive heart failure.单次静脉注射匹可托安对充血性心力衰竭的急性血流动力学影响。
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Eur J Clin Pharmacol. 1984;26(4):413-8. doi: 10.1007/BF00542133.
6
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7
Piretanide. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.吡咯他尼。对其药效学、药代动力学特性及治疗效果的初步综述。
Drugs. 1985 Jun;29(6):489-530. doi: 10.2165/00003495-198529060-00002.

本文引用的文献

1
On the clinical evaluation of diuretics with particular reference to a new phthalimidine diuretic, clorexolone.关于利尿剂的临床评价，特别提及一种新型邻苯二甲酰亚胺利尿剂氯噻酮。
Clin Pharmacol Ther. 1966 Mar-Apr;7(2):196-211. doi: 10.1002/cpt196672196.
2
Effect of frusemide on calcium excretion.速尿对钙排泄的影响。
Br Med J. 1969 Mar 22;1(5646):751-2. doi: 10.1136/bmj.1.5646.751.
3
The influence of hypertonic saline infusions upon the fractional reabsorption of urate and other ions in normal and hypertensive man.
Circulation. 1970 Jan;41(1):97-108. doi: 10.1161/01.cir.41.1.97.
4
The natural history of congestive heart failure: the Framingham study.充血性心力衰竭的自然病史：弗明汉姆研究
N Engl J Med. 1971 Dec 23;285(26):1441-6. doi: 10.1056/NEJM197112232852601.
5
Renal action, therapeutic use, and pharmacokinetics of the diuretic bumetanide.利尿剂布美他尼的肾脏作用、治疗用途及药代动力学
Clin Pharmacol Ther. 1974 Feb;15(2):141-55. doi: 10.1002/cpt1974152141.
6
Factors affecting urate excretion following diuretic administration in man.
Am J Med. 1969 Oct;47(4):564-74. doi: 10.1016/0002-9343(69)90187-9.
7
Relationship between urate retention and electrolyte excretion during treatment with loop diuretics [proceedings].袢利尿剂治疗期间尿酸潴留与电解质排泄的关系[会议论文集]
Br J Clin Pharmacol. 1977 Jun;4(3):392P. doi: 10.1111/j.1365-2125.1977.tb00740.x.
8
Effects of piretanide, bumetanide and frusemide on electrolyte and urate excretion in normal subjects.吡咯他尼、布美他尼和呋塞米对正常受试者电解质及尿酸盐排泄的影响。
Br J Clin Pharmacol. 1978 Aug;6(2):129-33. doi: 10.1111/j.1365-2125.1978.tb00837.x.
9
Kinetic and dynamic comparison of piretanide and furosemide.吡咯他尼与呋塞米的动力学和动态比较。
Clin Pharmacol Ther. 1978 May;23(5):558-65. doi: 10.1002/cpt1978235558.

匹拉噻米与布美他尼治疗充血性心力衰竭的单剂量比较

A single dose comparison of piretanide and bumetanide in congestive cardiac failure.

作者信息

Homeida M, Roberts C J, Dombey S L

出版信息

Br J Clin Pharmacol. 1979 Aug;8(2):173-8. doi: 10.1111/j.1365-2125.1979.tb05817.x.

DOI:10.1111/j.1365-2125.1979.tb05817.x
PMID:385025
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1429765/
Abstract

1 This study has compared the diuresis produced by a single oral administration of 6 mg piretanide, 9 mg piretanide and 1 mg bumetanide in a group of nine patients with cardiac failure using a balanced randomized design. 2 The natriuresis and kaliuresis produced in the first 6 h after administration of piretanide 9 mg and bumetanide 1 mg were similar. Piretanide 6 mg produced a lesser response. 3 There was evidence of sodium and water conservation following the diuresis for up to 48 h with all three treatments. 4 The patterns of urate and calcium excretion were similar for the two diuretics.

摘要
  1. 本研究采用平衡随机设计，比较了9名心力衰竭患者单次口服6毫克吡咯他尼、9毫克吡咯他尼和1毫克布美他尼后的利尿作用。2. 服用9毫克吡咯他尼和1毫克布美他尼后最初6小时内产生的利钠和利尿作用相似。6毫克吡咯他尼产生的反应较小。3. 所有三种治疗在利尿后长达48小时都有钠和水潴留的迹象。4. 两种利尿剂的尿酸和钙排泄模式相似。