匹拉噻米与布美他尼治疗充血性心力衰竭的单剂量比较
A single dose comparison of piretanide and bumetanide in congestive cardiac failure.
作者信息
Homeida M, Roberts C J, Dombey S L
出版信息
Br J Clin Pharmacol. 1979 Aug;8(2):173-8. doi: 10.1111/j.1365-2125.1979.tb05817.x.
Abstract
1 This study has compared the diuresis produced by a single oral administration of 6 mg piretanide, 9 mg piretanide and 1 mg bumetanide in a group of nine patients with cardiac failure using a balanced randomized design. 2 The natriuresis and kaliuresis produced in the first 6 h after administration of piretanide 9 mg and bumetanide 1 mg were similar. Piretanide 6 mg produced a lesser response. 3 There was evidence of sodium and water conservation following the diuresis for up to 48 h with all three treatments. 4 The patterns of urate and calcium excretion were similar for the two diuretics.
摘要
- 本研究采用平衡随机设计，比较了9名心力衰竭患者单次口服6毫克吡咯他尼、9毫克吡咯他尼和1毫克布美他尼后的利尿作用。2. 服用9毫克吡咯他尼和1毫克布美他尼后最初6小时内产生的利钠和利尿作用相似。6毫克吡咯他尼产生的反应较小。3. 所有三种治疗在利尿后长达48小时都有钠和水潴留的迹象。4. 两种利尿剂的尿酸和钙排泄模式相似。
相似文献
1
A single dose comparison of piretanide and bumetanide in congestive cardiac failure.
Br J Clin Pharmacol. 1979 Aug;8(2):173-8. doi: 10.1111/j.1365-2125.1979.tb05817.x.
2
Effects of piretanide, bumetanide and frusemide on electrolyte and urate excretion in normal subjects.
Br J Clin Pharmacol. 1978 Aug;6(2):129-33. doi: 10.1111/j.1365-2125.1978.tb00837.x.
3
Oral piretanide in chronic renal failure.
Br J Clin Pharmacol. 1982 Dec;14(6):857-60. doi: 10.1111/j.1365-2125.1982.tb02049.x.
4
Piretanide, a potent diuretic with potassium-sparing properties, for the treatment of congestive heart failure.
Clin Pharmacol Ther. 1986 Nov;40(5):587-94. doi: 10.1038/clpt.1986.228.
5
Efficacy and pharmacokinetics of piretanide in patients with congestive heart failure.
Eur J Clin Invest. 1989 Aug;19(4):378-83. doi: 10.1111/j.1365-2362.1989.tb00245.x.
6
Acute and long-term renal and metabolic effects of piretanide in congestive cardiac failure.
Br J Clin Pharmacol. 1988 Aug;26(2):143-54. doi: 10.1111/j.1365-2125.1988.tb03380.x.
7
Bumetanide in congestive heart failure.
Curr Med Res Opin. 1976;4(6):422-31. doi: 10.1185/03007997609111998.
8
[Clinical comparative trial of piretanide and furosemide in patients with advanced renal insufficiency. Drug levels and diuretic potency of single oral doses].
Arzneimittelforschung. 1983;33(9):1318-21.
9
The effects of piretanide, a potassium stable diuretic, on serum electrolytes in patients with congestive heart failure.
Pharmatherapeutica. 1985;4(5):288-95.
10
A comparative randomized double-blind clinical trial of bumetanide and furosemide in congestive cardiac failure and other edema states.
Int J Clin Pharmacol Ther Toxicol. 1984 Sep;22(9):473-8.
引用本文的文献
1
Assessment of natriuretic drugs.
Br J Clin Pharmacol. 1981 Oct;12(4):465-74. doi: 10.1111/j.1365-2125.1981.tb01252.x.
2
The effects of a combination of piretanide and triamterene in healthy subjects.
Br J Clin Pharmacol. 1981 Jan;11(1):106-8. doi: 10.1111/j.1365-2125.1981.tb01117.x.
3
Oral piretanide in chronic renal failure.
Br J Clin Pharmacol. 1982 Dec;14(6):857-60. doi: 10.1111/j.1365-2125.1982.tb02049.x.
4
Acute haemodynamic effects of a single intravenous dose of piretanide in congestive heart failure.
Eur J Clin Pharmacol. 1983;24(2):163-7. doi: 10.1007/BF00613811.
5
Comparison of the short-term effects of the loop diuretic piretanide and furosemide in patients with renal insufficiency.
Eur J Clin Pharmacol. 1984;26(4):413-8. doi: 10.1007/BF00542133.
6
Bumetanide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use.
Drugs. 1984 Nov;28(5):426-64. doi: 10.2165/00003495-198428050-00003.
7
Piretanide. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
Drugs. 1985 Jun;29(6):489-530. doi: 10.2165/00003495-198529060-00002.
本文引用的文献
1
On the clinical evaluation of diuretics with particular reference to a new phthalimidine diuretic, clorexolone.
Clin Pharmacol Ther. 1966 Mar-Apr;7(2):196-211. doi: 10.1002/cpt196672196.
2
Effect of frusemide on calcium excretion.
Br Med J. 1969 Mar 22;1(5646):751-2. doi: 10.1136/bmj.1.5646.751.
3
The influence of hypertonic saline infusions upon the fractional reabsorption of urate and other ions in normal and hypertensive man.
Circulation. 1970 Jan;41(1):97-108. doi: 10.1161/01.cir.41.1.97.
4
The natural history of congestive heart failure: the Framingham study.
N Engl J Med. 1971 Dec 23;285(26):1441-6. doi: 10.1056/NEJM197112232852601.
5
Renal action, therapeutic use, and pharmacokinetics of the diuretic bumetanide.
Clin Pharmacol Ther. 1974 Feb;15(2):141-55. doi: 10.1002/cpt1974152141.
6
Factors affecting urate excretion following diuretic administration in man.
Am J Med. 1969 Oct;47(4):564-74. doi: 10.1016/0002-9343(69)90187-9.
7
Relationship between urate retention and electrolyte excretion during treatment with loop diuretics [proceedings].
Br J Clin Pharmacol. 1977 Jun;4(3):392P. doi: 10.1111/j.1365-2125.1977.tb00740.x.
8
Effects of piretanide, bumetanide and frusemide on electrolyte and urate excretion in normal subjects.
Br J Clin Pharmacol. 1978 Aug;6(2):129-33. doi: 10.1111/j.1365-2125.1978.tb00837.x.
9
Kinetic and dynamic comparison of piretanide and furosemide.
Clin Pharmacol Ther. 1978 May;23(5):558-65. doi: 10.1002/cpt1978235558.
Zotero 插件