慢性肾衰竭中口服布美他尼的应用
Oral piretanide in chronic renal failure.
作者信息
Henderson I S, Beattie T J, Kennedy A C, Dombey S L
出版信息
Br J Clin Pharmacol. 1982 Dec;14(6):857-60. doi: 10.1111/j.1365-2125.1982.tb02049.x.
Abstract
1 The effects of high doses of piretanide, a new diuretic agent chemically related to frusemide and bumetanide were evaluated in twelve patients with severe chronic renal insufficiency (creatinine clearance below 25 ml/min). 2 Patients received either 30 mg or 60 mg piretanide orally after a water load of 11. Urine volume and the excretion of electrolytes, creatinine, urea and uric acid were measured over the subsequent 24 h. 3 Piretanide produced an effective diuresis and natriuresis in these patients, its action being broadly similar to those of bumetanide and frusemide observed in previous studies.
摘要
- 对12例严重慢性肾功能不全（肌酐清除率低于25ml/分钟）患者评估了高剂量的吡咯他尼（一种化学结构与速尿和布美他尼相关的新型利尿剂）的作用。2. 患者在摄入11的水负荷后口服30mg或60mg吡咯他尼。在随后的24小时内测量尿量以及电解质、肌酐、尿素和尿酸的排泄量。3. 吡咯他尼在这些患者中产生了有效的利尿和利钠作用，其作用与先前研究中观察到的布美他尼和速尿的作用大致相似。
相似文献
1
Oral piretanide in chronic renal failure.慢性肾衰竭中口服布美他尼的应用
Br J Clin Pharmacol. 1982 Dec;14(6):857-60. doi: 10.1111/j.1365-2125.1982.tb02049.x.
2
Effects of piretanide, bumetanide and frusemide on electrolyte and urate excretion in normal subjects.吡咯他尼、布美他尼和呋塞米对正常受试者电解质及尿酸盐排泄的影响。
Br J Clin Pharmacol. 1978 Aug;6(2):129-33. doi: 10.1111/j.1365-2125.1978.tb00837.x.
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[Bumetanide, a new diuretic active during chronic renal failure (author's transl)].布美他尼，一种在慢性肾衰竭时有效的新型利尿剂（作者译）
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A single dose comparison of piretanide and bumetanide in congestive cardiac failure.匹拉噻米与布美他尼治疗充血性心力衰竭的单剂量比较
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Comparison of the short-term effects of the loop diuretic piretanide and furosemide in patients with renal insufficiency.肾功能不全患者中襻利尿剂匹可他尼与呋塞米短期疗效比较。
Eur J Clin Pharmacol. 1984;26(4):413-8. doi: 10.1007/BF00542133.
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Renal actions of piretanide and three other "loop" diuretics.吡咯他尼及其他三种“袢”利尿剂的肾脏作用
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引用本文的文献
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Piretanide. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.吡咯他尼。对其药效学、药代动力学特性及治疗效果的初步综述。
Drugs. 1985 Jun;29(6):489-530. doi: 10.2165/00003495-198529060-00002.
本文引用的文献
1
STUDIES ON ETHACRYNIC ACID IN PATIENTS WITH REFRACTORY EDEMA.难治性水肿患者的依他尼酸研究。
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Effects of reduced glomerular filtration rate on responsiveness to chlorothiazide and mercurial diuretics.肾小球滤过率降低对氯噻嗪和汞利尿剂反应性的影响。
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Activity of a new high efficiency diuretic in man: piretanide (HOE 118).一种新型高效利尿剂在人体中的活性：吡咯他尼（HOE 118）。
Br J Clin Pharmacol. 1980 Jun;9(6):577-83. doi: 10.1111/j.1365-2125.1980.tb01083.x.
4
Diuretics in chronic renal disease: a study of high dosage frusemide.慢性肾病中的利尿剂：大剂量速尿的研究
Clin Sci. 1971 Sep;41(3):171-87. doi: 10.1042/cs0410171.
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High dosage metolazone in chronic renal failure.高剂量美托拉宗治疗慢性肾衰竭
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6
Diuretic properties of furosemide in renal disease.呋塞米在肾脏疾病中的利尿特性。
Ann Intern Med. 1968 Aug;69(2):249-61. doi: 10.7326/0003-4819-69-2-249.
7
Oral bumetanide in chronic renal failure.口服布美他尼治疗慢性肾衰竭
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8
Effects of piretanide, bumetanide and frusemide on electrolyte and urate excretion in normal subjects.吡咯他尼、布美他尼和呋塞米对正常受试者电解质及尿酸盐排泄的影响。
Br J Clin Pharmacol. 1978 Aug;6(2):129-33. doi: 10.1111/j.1365-2125.1978.tb00837.x.
9
A single dose comparison of piretanide and bumetanide in congestive cardiac failure.匹拉噻米与布美他尼治疗充血性心力衰竭的单剂量比较
Br J Clin Pharmacol. 1979 Aug;8(2):173-8. doi: 10.1111/j.1365-2125.1979.tb05817.x.
10
Piretanide (HOE 118): a new potent diuretic: preliminary communication.吡咯他尼（HOE 118）：一种新型强效利尿剂：初步通讯
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