Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan.
Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan.
J Gastrointest Surg. 2024 May;28(5):719-724. doi: 10.1016/j.gassur.2024.02.026. Epub 2024 Mar 1.
Common bile duct (CBD) stones commonly occur in cholecystectomy cases. The management options include laparoscopic CBD exploration (LCBDE) or endoscopic retrograde cholangiopancreatography (ERCP) followed by laparoscopic cholecystectomy (LC). Although ERCP is fully developed, it has complications, and LCBDE is a proven alternative. This study aimed to evaluate the safety and efficacy of these treatments in elderly individuals aged ≥70 years.
A retrospective study between January 2015 and July 2022 included 160 elderly patients (aged ≥70 years) diagnosed with cholelithiasis and choledocholithiasis. The patients were divided into 1-stage (LCBDE [n = 80]) or 2-stage (ERCP followed by LC [n = 80]) treatment groups. Data collected encompassed comorbidities, symptoms, bile duct clearance, postoperative complications, and long-term outcomes for systematic analysis.
This study analyzed 160 patients treated for CBD stones, comparing 1-stage and 2-stage groups. The 1-stage group had more female patients than the 2-stage group (57.5% vs 37.5%, respectively). The 1-stage group had a mean age of 80.55 ± 7.00 years, which was higher than the mean age in the 2-stage group. American Society of Anesthesiologists classification, Charlson Comorbidity Index, and laboratory findings were similar. Pancreatitis and cholangitis occurred after ERCP in the 2-stage group. Stone clearance rates (92.35% [1-stage group] vs 95.00% [2-stage group]) and biliary leakage incidence (7.5% [1-stage group] vs 3.0% [2-stage group]) were similar, as were postoperative complications and long-term recurrence rates (13.0% [1-stage group] vs 12.5% [2-stage group]).
Our research indicates that both the combination of LCBDE and LC and the sequence of ERCP followed by LC are equally efficient and secure when treating CBD stones in elderly patients. Consequently, the 1-stage procedure may be considered the preferred treatment approach for this demographic.
胆总管(CBD)结石在胆囊切除术病例中很常见。治疗选择包括腹腔镜胆总管探查术(LCBDE)或内镜逆行胰胆管造影术(ERCP)联合腹腔镜胆囊切除术(LC)。尽管 ERCP 技术已经很成熟,但仍存在并发症,LCBDE 是一种经过验证的替代方法。本研究旨在评估这些治疗方法在≥70 岁老年患者中的安全性和有效性。
回顾性研究,纳入 2015 年 1 月至 2022 年 7 月期间诊断为胆石症和胆总管结石的 160 例老年患者(年龄≥70 岁)。患者分为 1 期(LCBDE [n=80])或 2 期(ERCP 后 LC [n=80])治疗组。收集的数据包括合并症、症状、胆管清除情况、术后并发症和长期结果,以便进行系统分析。
本研究分析了 160 例 CBD 结石患者,比较了 1 期和 2 期治疗组。1 期组中女性患者多于 2 期组(分别为 57.5%和 37.5%)。1 期组患者的平均年龄为 80.55±7.00 岁,高于 2 期组。美国麻醉医师协会(ASA)分级、Charlson 合并症指数和实验室检查结果相似。2 期组 ERCP 后发生胰腺炎和胆管炎。结石清除率(92.35%[1 期组]与 95.00%[2 期组])和胆漏发生率(7.5%[1 期组]与 3.0%[2 期组])相似,术后并发症和长期复发率(13.0%[1 期组]与 12.5%[2 期组])也相似。
我们的研究表明,LCBDE 联合 LC 与 ERCP 联合 LC 序贯治疗老年患者 CBD 结石同样有效且安全。因此,1 期手术可能是该人群的首选治疗方法。