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老年患者腹腔镜胆总管探查一期缝合的临床安全性研究:一种治疗结石的新策略

Clinical safety study of laparoscopic common bile duct exploration and primary suture in elderly patients: a new strategy for the treatment of stones.

作者信息

Ye Hai-Wen, Liu Fei, Gu Dai-Jiao, Liao Jie, Huang Rong-Sen, Pan Jun-Jiang

机构信息

Department of General Surgery, the Second People's Hospital of Yibin, Yibin, Sichuan, 644000, China.

出版信息

BMC Surg. 2025 Aug 30;25(1):401. doi: 10.1186/s12893-025-03146-7.


DOI:10.1186/s12893-025-03146-7
PMID:40883709
Abstract

BACKGROUND: Laparoscopic common bile duct exploration and primary suture (LBEPS) offers advantages such as minimal invasion, shorter operative time, and faster postoperative recovery in the treatment of common bile duct stones.However, its safety in elderly patients remains controversial. METHODS: A retrospective analysis was conducted on the clinical data of 128 patients with common bile duct stones who underwent LBEPS treatment in our hospital from December 2018 to March 2025.The patients were divided into an elderly group (≥ 65years, n = 55) and a non-elderly group (< 65years, n = 73) based on age.Baseline characteristics, operative time, postoperative complications, recurrence rate, and other indicators were compared between the two groups. RESULTS: There were no significant differences in baseline characteristics, such as sex, body mass index(BMI), or stone diameter, between the two groups (P > 0.05). The diameter of the common bile duct was significantly larger in the elderly group compared to the non-elderly group (P < 0.05). There were no significant differences in alanine aminotransferase (ALT), aspartate aminotransferase(AST), total bilirubi (TB), direct bilirubin (DB), white blood cells (WBC), haemoglobin (HGB), or platelet (PLT) levels between the two groups before and after surgery(P > 0.05). However, the postoperative drainage time and total hospital stay were longer in the elderly group (P < 0.05). The presence of hepatitis B was identified as an independent risk factor for complications after LBEPS. CONCLUSION: The clinical application of LBEPS in elderly patients with common bile duct stones is safe and feasible.Elderly patients require a longer preoperative length of stay compared to non-elderly patients.Patients with common bile duct stones and concomitant hepatitis B are more prone to complications after LBEPS.

摘要

背景:腹腔镜胆总管探查一期缝合术(LBEPS)在胆总管结石治疗中具有微创、手术时间短、术后恢复快等优点。然而,其在老年患者中的安全性仍存在争议。 方法:回顾性分析2018年12月至2025年3月在我院接受LBEPS治疗的128例胆总管结石患者的临床资料。根据年龄将患者分为老年组(≥65岁,n = 55)和非老年组(<65岁,n = 73)。比较两组患者的基线特征、手术时间、术后并发症、复发率等指标。 结果:两组患者在性别、体重指数(BMI)、结石直径等基线特征方面无显著差异(P > 0.05)。老年组胆总管直径明显大于非老年组(P < 0.05)。两组患者手术前后丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、总胆红素(TB)、直接胆红素(DB)、白细胞(WBC)、血红蛋白(HGB)或血小板(PLT)水平无显著差异(P > 0.05)。然而,老年组术后引流时间和总住院时间较长(P < 0.05)。乙型肝炎的存在被确定为LBEPS术后并发症的独立危险因素。 结论:LBEPS在老年胆总管结石患者中的临床应用是安全可行的。与非老年患者相比,老年患者术前住院时间更长。合并乙型肝炎的胆总管结石患者LBEPS术后更容易发生并发症。

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本文引用的文献

[1]
Impact of a positive end-expiratory pressure on oxygenation, respiratory compliance, and hemodynamics in obese patients undergoing laparoscopic surgery in reverse Trendelenburg position: a systematic review and meta-analysis of randomized controlled trials.

BMC Anesthesiol. 2025-2-7

[2]
Research Progress on Frailty in Elderly People.

Clin Interv Aging. 2024

[3]
Association of preoperative antiviral treatment with incidences of post-hepatectomy liver failure in hepatitis B virus-related hepatocellular carcinoma.

World J Gastrointest Surg. 2024-7-27

[4]
Comparison of laparoscopic common bile duct exploration plus cholecystectomy and endoscopic retrograde cholangiopancreatography followed by laparoscopic cholecystectomy for elderly patients with common bile duct stones and gallbladder stones.

J Gastrointest Surg. 2024-5

[5]
ERCP for common bile duct stones in the elderly: refining the procedure to improve outcomes.

Rev Esp Enferm Dig. 2024-5

[6]
Contemporary management of common bile duct stone: What you need to know.

J Trauma Acute Care Surg. 2023-12-1

[7]
Laparoscopic common bile duct exploration with primary closure could be safely performed among elderly patients with choledocholithiasis.

BMC Geriatr. 2023-8-11

[8]
Evidence-based clinical practice guidelines for cholelithiasis 2021.

J Gastroenterol. 2023-9

[9]
Impact of Hepatitis B virus infection on postoperative complications and length of stay in elderly patients with hip fracture: A retrospective cohort study.

Injury. 2023-7

[10]
The Outcome and Safety in Laparoscopic Common Bile Duct Exploration with Primary Suture versus T-Tube Drainage: A Meta-Analysis.

Appl Bionics Biomech. 2023-2-7

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