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用于 STIs/HIV 预测的轻量级联邦学习。

Lightweight federated learning for STIs/HIV prediction.

机构信息

School of Mathematics, Physics and Computing, Centre for Health Research, University of Southern Queensland, Toowoomba Campus, Toowoomba, 4350, QLD, Australia.

School of Computing Technologies, RMIT University, GPO Box 2476, Melbourne, 3001, VIC, Australia.

出版信息

Sci Rep. 2024 Mar 19;14(1):6560. doi: 10.1038/s41598-024-56115-0.

DOI:10.1038/s41598-024-56115-0
PMID:38503789
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10950866/
Abstract

This paper presents a solution that prioritises high privacy protection and improves communication throughput for predicting the risk of sexually transmissible infections/human immunodeficiency virus (STIs/HIV). The approach utilised Federated Learning (FL) to construct a model from multiple clinics and key stakeholders. FL ensured that only models were shared between clinics, minimising the risk of personal information leakage. Additionally, an algorithm was explored on the FL manager side to construct a global model that aligns with the communication status of the system. Our proposed method introduced Random Forest Federated Learning for assessing the risk of STIs/HIV, incorporating a flexible aggregation process that can be adjusted to accommodate the capacious communication system. Experimental results demonstrated the significant potential of a solution for estimating STIs/HIV risk. In comparison with recent studies, our approach yielded superior results in terms of AUC (0.97) and accuracy ( ). Despite these promising findings, a limitation of the study lies in the experiment for man's data, due to the self-reported nature of the data and sensitive content. which may be subject to participant bias. Future research could check the performance of the proposed framework in partnership with high-risk populations (e.g., men who have sex with men) to provide a more comprehensive understanding of the proposed framework's impact and ultimately aim to improve health outcomes/health service optimisation.

摘要

本文提出了一种解决方案,该方案优先考虑高度隐私保护,并提高预测性传播感染/人类免疫缺陷病毒 (STIs/HIV) 风险的通信吞吐量。该方法利用联邦学习 (FL) 从多个诊所和主要利益相关者构建模型。FL 确保仅在诊所之间共享模型,最大限度地降低个人信息泄露的风险。此外,还在 FL 管理器端探索了一种算法,以构建与系统通信状态一致的全局模型。我们提出的方法引入了随机森林联邦学习来评估 STIs/HIV 的风险,其中包含一个灵活的聚合过程,可以根据需要进行调整以适应大容量的通信系统。实验结果表明,该解决方案在估计 STIs/HIV 风险方面具有显著的潜力。与最近的研究相比,我们的方法在 AUC(0.97)和准确性( )方面取得了更好的结果。尽管取得了这些有希望的发现,但该研究的一个局限性在于对男性数据的实验,因为数据具有自我报告的性质,并且内容敏感,可能会受到参与者偏见的影响。未来的研究可以与高危人群(例如,男男性接触者)合作,检验所提出框架的性能,以更全面地了解所提出框架的影响,并最终旨在改善健康结果/优化卫生服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/8e54ce948824/41598_2024_56115_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/ce312b89c273/41598_2024_56115_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/112b275cb379/41598_2024_56115_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/f311b9aa123b/41598_2024_56115_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/c35aed5ac2df/41598_2024_56115_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/8d8d4bd6c411/41598_2024_56115_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/18b2ebab32ca/41598_2024_56115_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/8e54ce948824/41598_2024_56115_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/ce312b89c273/41598_2024_56115_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/112b275cb379/41598_2024_56115_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/f311b9aa123b/41598_2024_56115_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/c35aed5ac2df/41598_2024_56115_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/8d8d4bd6c411/41598_2024_56115_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/18b2ebab32ca/41598_2024_56115_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4234/10950866/8e54ce948824/41598_2024_56115_Fig6_HTML.jpg

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