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验证术后恢复质量 15 问卷在急诊手术后的有效性及其与术后三个月生活质量的关系。

Validation of the postoperative Quality of Recovery-15 questionnaire after emergency surgery and association with quality of life at three months.

机构信息

Department of Anesthesia and Intensive Care, Faculty of Health, Angers University Hospital, Angers, France.

Department of Orthopaedics, Angers University Hospital, Angers, France.

出版信息

Can J Anaesth. 2024 May;71(5):590-599. doi: 10.1007/s12630-024-02722-4. Epub 2024 Mar 19.

DOI:10.1007/s12630-024-02722-4
PMID:38504036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11026244/
Abstract

PURPOSE

The Quality of Recovery-15 (QoR-15) tool, validated for measuring postoperative recovery following scheduled surgeries, has not been psychometrically assessed in emergency contexts. Moreover, the QoR-15's associations with long-term outcomes remain underexplored. This study aimed to confirm the validity and reliability of the QoR-15 following emergency surgery and assess its association with three-month postoperative quality of life.

METHODS

We conducted a prospective cohort study (August 2021-April 2022) on adult patients who underwent emergency surgery. The QoR-15 questionnaire was administered before surgery (H0) and at 24 hr (H24) and 48 hr (H48) after surgery. We examined the H24 score's associations with both the three-month quality of life, as assessed by the EQ-5D scale, and the number of days spent at home at 30 (DAH30) and 90 (DAH90) days.

RESULTS

Of the 375 included patients, 352 (94%) completed the QoR-15 at H24 and 338 (90%) were followed up at three months. The population represented the following diverse surgical specialties: orthopedic (51%), gastrointestinal (27%), urologic (13%), and others (9%). The QoR-15 questionnaire confirmed all psychometric qualities (internal consistency, reproducibility, responsiveness, acceptability, construct, and convergent validities) in the emergency context. The average minimum clinical difference was 8.0 at H24. There was an association between QoR-15 at H24 and the three-month quality of life (r = 0.24; 95% confidence interval [CI], 0.14 to 0.34; P < 0.001), DAH30 (r = 0.33; 95% CI, 0.23 to 0.41; P < 0.001), and DAH90 (r = 0.31; 95% CI, 0.22 to 0.40; P < 0.001).

CONCLUSION

The QoR-15 score is valid for measuring early postoperative recovery after emergency surgery. The H24 score significantly correlated with both the three-month quality of life and the number of days at home.

STUDY REGISTRATION

ClinicalTrials.gov (NCT04845763); first submitted 11 April 2021.

摘要

目的

用于测量择期手术后恢复情况的术后恢复质量-15 (QoR-15)工具,其在急诊环境中的心理测量学评估尚未得到验证。此外,QoR-15 与长期结局的相关性仍未得到充分探索。本研究旨在确认 QoR-15 在急诊手术后的有效性和可靠性,并评估其与术后三个月生活质量的相关性。

方法

我们进行了一项前瞻性队列研究(2021 年 8 月至 2022 年 4 月),纳入了接受急诊手术的成年患者。QoR-15 问卷在术前(H0)和术后 24 小时(H24)和 48 小时(H48)进行评估。我们研究了 H24 评分与术后三个月的生活质量(通过 EQ-5D 量表评估)和术后 30 天(DAH30)和 90 天(DAH90)在家天数的相关性。

结果

375 名纳入患者中,352 名(94%)在 H24 时完成了 QoR-15 问卷,338 名(90%)在三个月时进行了随访。该人群代表了以下多样化的外科专业:骨科(51%)、胃肠科(27%)、泌尿科(13%)和其他科室(9%)。QoR-15 问卷在急诊环境中证实了所有心理测量学特性(内部一致性、可重复性、反应性、可接受性、结构和收敛有效性)。H24 的平均最小临床差异为 8.0。H24 的 QoR-15 评分与术后三个月的生活质量(r=0.24;95%置信区间 [CI],0.14 至 0.34;P<0.001)、DAH30(r=0.33;95% CI,0.23 至 0.41;P<0.001)和 DAH90(r=0.31;95% CI,0.22 至 0.40;P<0.001)存在相关性。

结论

QoR-15 评分可有效评估急诊手术后早期的术后恢复情况。H24 评分与术后三个月的生活质量和在家天数均显著相关。

研究注册

ClinicalTrials.gov(NCT04845763);首次提交日期为 2021 年 4 月 11 日。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d48c/11026244/faf8c195c863/12630_2024_2722_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d48c/11026244/b2a342b5f089/12630_2024_2722_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d48c/11026244/ab3a1f31a043/12630_2024_2722_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d48c/11026244/faf8c195c863/12630_2024_2722_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d48c/11026244/b2a342b5f089/12630_2024_2722_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d48c/11026244/ab3a1f31a043/12630_2024_2722_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d48c/11026244/faf8c195c863/12630_2024_2722_Fig3_HTML.jpg

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