Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education, Guilin 541004, China; Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin 541004, China; Guangxi Key Laboratory of Environmental Processes and Remediation in Ecologically Fragile Regions, China.
Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education, Guilin 541004, China; Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin 541004, China; Guangxi Key Laboratory of Environmental Processes and Remediation in Ecologically Fragile Regions, China.
Food Chem. 2024 Jul 30;447:139041. doi: 10.1016/j.foodchem.2024.139041. Epub 2024 Mar 15.
In this paper, a new Pd metal organic framework (PdMOF) surface molecularly imprinted polyaniline nanocatalytic probe (PdMOF@MIP) with dual functions of recognition and catalysis was synthesized. It is found that the PdMOF@MIP nanoprobe can not only identify OTC but also catalyze the new nanoreaction of NaHPO-HAuCl to generate gold nanoparticles (AuNPs), and the generated AuNPs could be traced by surface-enhanced Raman scattering (SERS). When OTC specifically binds to PdMOF@MIP to generate PdMOF@MIP-OTC conjugate, its catalytic effect is weakened and the analytical signal is reduced linaerly. Accordingly, a new, highly sensitive, selective and simple SERS/RRS/Abs trimode detection platform for OTC was constructed. The linear range of SERS was 0.0625 ng/mL ∼ 1.75 ng/mL and the limit of detection was 0.015 ng/mL. This new nanocatalytic probe detection strategy can also be used for the selective detection of other antibiotics such as tetracycline and doxycycline, respectively. In addition, the nanocatalytic mechanism has been investigated.
本文合成了一种具有识别和催化双重功能的新型 Pd 金属有机骨架（PdMOF）表面分子印迹聚苯胺纳米催化探针（PdMOF@MIP）。研究发现，PdMOF@MIP 纳米探针不仅可以识别 OTC，还可以催化 NaHPO-HAuCl 的新纳米反应生成金纳米粒子（AuNPs），生成的 AuNPs 可以通过表面增强拉曼散射（SERS）进行跟踪。当 OTC 特异性结合到 PdMOF@MIP 上生成 PdMOF@MIP-OTC 缀合物时，其催化效果减弱，分析信号线性降低。因此，构建了一种新的、高灵敏度、选择性和简单的 SERS/RRS/Abs 三模态检测平台用于检测 OTC。SERS 的线性范围为 0.0625ng/mL~1.75ng/mL，检测限为 0.015ng/mL。这种新的纳米催化探针检测策略还可以分别用于选择性检测其他抗生素，如四环素和强力霉素。此外，还研究了纳米催化机制。
