State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, China; Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education, Guilin, 541004, China; Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin, 541004, China; College of Pharmacy, Guilin Medical University, Guilin, 541199, China.
State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, China; Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University), Ministry of Education, Guilin, 541004, China; Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin, 541004, China.
Biosens Bioelectron. 2022 Dec 1;217:114743. doi: 10.1016/j.bios.2022.114743. Epub 2022 Sep 22.
A new MXene supported Pd nanoparticles (TiC@Pd) nanosol with good stability and strong catalysis was prepared by the two-step procedure. Experiment was found that TiC@Pd could strongly catalyze the reduction of HAuCl by HO to produce gold nanoparticles (AuNPs), with strong surface enhanced Raman scattering (SERS), resonance Rayleigh scattering (RRS) and surface plasmon resonance absorption (Abs). Coupled this new SERS/RRS/Abs trimode nanocatalytic indicator reaction with specific TNT polypeptide (PT), a facile and selective trimode polypeptide biosensoring platform was established for the detection of ultratrace TNT, with a linear range of 1.1-66, 1.1-66 and 4.4-66 pmol/L TNT, and detection limit (DL) of 0.69, 0.97 and 3.36 pmol/L by SERS, RRS and Abs assay respectively. It has been used to detect TNT in wastewater and soil samples, with recovery of 98.7-106% and RSD of 6.22-8.77%. In addition, this biosensoring platform can be also used to assay glyphosate and estradiol, respectively.
通过两步法制备了一种具有良好稳定性和强催化性的新型 MXene 负载 Pd 纳米粒子（TiC@Pd）纳米溶胶。实验发现 TiC@Pd 可强烈催化 HO 将 HAuCl 还原为金纳米粒子（AuNPs），具有强表面增强拉曼散射（SERS）、共振瑞利散射（RRS）和表面等离子体共振吸收（Abs）。将这种新的 SERS/RRS/Abs 三模态纳米催化指标反应与特定的 TNT 多肽（PT）结合，建立了一种用于检测痕量 TNT 的简便、选择性的三模态多肽生物传感平台，其线性范围分别为 1.1-66、1.1-66 和 4.4-66 pmol/L TNT，SERS、RRS 和 Abs 测定的检测限（DL）分别为 0.69、0.97 和 3.36 pmol/L。该方法已用于检测废水和土壤样品中的 TNT，回收率为 98.7-106%，相对标准偏差为 6.22-8.77%。此外，该生物传感平台还可分别用于测定草甘膦和雌二醇。
