Laumonier R
Bull Cancer. 1979;66(3):307-16.
An overall survey of the transitional epithelium of the bladder and its carcinomas. This study is based upon the recent literature, in particular the considerable contribution of scanner electron microscopy. a) The transitional epithelium has the reputation of having a simple structure and even behaviour. In fact, it is complex with highly specialised surface cells. It has marked powers of regeneration after aggressions of various types. b) Tumours of the transitional epithelium are defined in relation to rupture of the basal lamina. Invasive carcinomas are classified according to their histological stage of penetration, their pure or partially metaplasic type and their degree defined according to the criteria of Broders. There exists a correlation between these three types of evaluation. Non-invasive carcinomas are either papillary--putting into question the reality of benign bladder papilloma--or flat mucosal and then often associated closely or at a distance with an invasive carcinoma. c) Abnormal regeneration, dysplasia or hyperplasia as a result of aggressions of different types or developing in isolation represent a high risk histologically, implying the need for careful follow-up and surveillance. d) Histopathological study of urothelial or transitional tumours is simple in operative specimens but difficult in biopsies. It requires close cooperation between surgeons and pathologists to ensure correct orientation of the fragments.
膀胱移行上皮及其癌的全面综述。本研究基于近期文献，特别是扫描电子显微镜的重大贡献。a) 移行上皮素有结构简单、行为一致的名声。实际上，它很复杂，有高度特化的表面细胞。在遭受各种类型的侵害后，它有显著的再生能力。b) 移行上皮肿瘤是根据基底层的破裂来定义的。浸润性癌根据其组织学浸润阶段、纯型或部分化生型以及根据布罗德斯标准定义的分级进行分类。这三种评估类型之间存在相关性。非浸润性癌要么是乳头状的——这使膀胱良性乳头状瘤的真实性受到质疑——要么是扁平黏膜型，然后常常与浸润性癌密切或远距离相关。c) 由于不同类型的侵害或孤立发生而导致的异常再生、发育异常或增生在组织学上代表高风险，这意味着需要仔细的随访和监测。d) 尿路上皮或移行性肿瘤的组织病理学研究在手术标本中很简单，但在活检中很难。它需要外科医生和病理学家密切合作以确保碎片的正确定向。
